Description

5-Bromo-3-Fluoro-2-Methoxyaniline is a high-purity aromatic amine derivative, distinguished by its halogen and methoxy substituents, which make it a versatile and valuable building block in advanced organic synthesis. Its primary value lies in its role as a key intermediate for constructing complex molecules with specific electronic and steric properties. This compound is essential for R&D and production chemists in the pharmaceutical, agrochemical, and material science industries, where it is used to develop new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders, oncology, and anti-infective therapies.
• Agrochemical Synthesis: Serves as a key building block for developing new-generation herbicides, fungicides, and insecticides, leveraging the fluorine and bromine atoms for enhanced bioactivity and environmental stability.
• Material Science Research: Used in the development of organic semiconductors, liquid crystals, and advanced polymers, where its aniline core and substituents contribute to tailored electronic properties.
• Dye and Pigment Manufacturing: Acts as an intermediate for synthesizing specialized azo dyes and pigments, providing unique color properties and lightfastness.
• Cross-Coupling Reactions: An excellent substrate for palladium-catalyzed cross-coupling reactions (e.g., Buchwald-Hartwig amination, Suzuki reactions) to create complex biaryl and amine structures.

Basic Information

Product Name	5-Bromo-3-Fluoro-2-Methoxyaniline
CAS No.	239122-51-1
Molecular Formula	C7H7BrFNO
Molecular Weight	220.04 g/mol
Synonyms	2-Methoxy-5-bromo-3-fluoroaniline; 3-Fluoro-5-bromo-2-methoxyaniline; 5-Bromo-3-fluoro-2-methoxybenzenamine; 2-Amino-4-bromo-6-fluoroanisole; Benzenamine, 5-bromo-3-fluoro-2-methoxy-; 239122-51-1
EINECS	Contact for details

Quality Control

Every batch of 5-Bromo-3-Fluoro-2-Methoxyaniline is manufactured and tested under a strict quality management system. Our products undergo rigorous quality testing, including HPLC, GC, and NMR analysis, to ensure compliance with industry standards and customer specifications. Certificates of Analysis (COA) documenting purity, identity, and impurity profiles are available upon request. We support cGMP and ISO standards for pharmaceutical and industrial applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its light-sensitive and easily oxidized nature, it is recommended to store the material under an inert atmosphere (e.g., nitrogen or argon) for long-term stability. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Off-white to light brown crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.