Description

2-Fluoro-4-(Trifluoromethyl)Benzyl Bromide is a high-value, multi-functional benzyl bromide derivative that serves as a critical building block in advanced organic synthesis. Its molecular structure, featuring both fluorine and trifluoromethyl groups, imparts unique electronic and steric properties essential for modifying the pharmacokinetic profiles of target molecules. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical sectors for the synthesis of novel active ingredients, including potential drug candidates and advanced crop protection agents.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in fluorinated drug discovery programs targeting CNS disorders, oncology, and anti-infectives.
• Agrochemical Synthesis: Used in the manufacture of advanced herbicides, fungicides, and insecticides, where the fluorine and trifluoromethyl groups enhance biological activity and environmental stability.
• Liquid Crystal & OLED Materials: Serves as a precursor for fluorinated aromatic compounds used in electronic display technologies and organic light-emitting diodes (OLEDs).
• Functional Material Research: Employed in academic and industrial R&D for creating novel polymers, ligands, and specialty chemicals with tailored properties.
• Cross-Coupling Reactions: Acts as an efficient electrophile in Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions to construct complex biaryl systems.

Basic Information

Item	Detail
Product Name	2-Fluoro-4-(Trifluoromethyl)Benzyl Bromide
CAS No.	239087-07-1
Molecular Formula	C8H5BrF4
Molecular Weight	257.03 g/mol
Synonyms	1-(Bromomethyl)-2-fluoro-4-(trifluoromethyl)benzene; α-Bromo-2-fluoro-α,α,α-trifluoro-p-xylene; 2-Fluoro-α-(bromomethyl)-α,α,α-trifluorotoluene; (2-Fluoro-4-(trifluoromethyl)phenyl)methyl bromide; 4-(Bromomethyl)-3-fluorobenzotrifluoride; 2-Fluoro-4-trifluoromethylbenzyl bromide; F-TFM-BnBr
EINECS	Contact for details

Quality Control

Every batch of 2-Fluoro-4-(Trifluoromethyl)Benzyl Bromide is manufactured and tested under a strict quality management system. We guarantee high-purity material suitable for demanding synthetic applications, with comprehensive in-process and final release testing. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to ensure full traceability and compliance with your internal quality standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong acids, bases, and oxidizing agents. Due to its light-sensitive nature and reactivity, it is recommended to store under an inert atmosphere for long-term preservation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.