Description

2-Fluoro-6-(Trifluoromethyl)Benzylamine CAS NO 239087-06-0 is a high-value fluorinated aromatic amine building block, prized for its unique combination of fluorine atoms and a reactive benzylamine group. This compound is critical for introducing specific steric and electronic properties into target molecules, directly impacting their biological activity and physicochemical profile. It is an essential intermediate for researchers and manufacturers in the pharmaceutical and agrochemical sectors, where precise molecular design is paramount for developing new active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of novel active pharmaceutical ingredients (APIs), particularly for CNS drugs, anti-infectives, and oncology therapeutics.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides, where the fluorine atoms enhance lipophilicity and metabolic stability.
• Ligand & Catalyst Development: Serves as a precursor for creating specialized ligands in asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science: Incorporated into the synthesis of specialty polymers, liquid crystals, and advanced electronic materials to modify thermal and optical properties.
• Fluorine Chemistry Research: A valuable substrate for studying structure-activity relationships (SAR) and developing new fluorination methodologies in academic and industrial R&D.

Basic Information

Product Name	2-Fluoro-6-(Trifluoromethyl)Benzylamine
CAS No.	239087-06-0
Molecular Formula	C8H7F4N
Molecular Weight	193.14 g/mol
Synonyms	(2-Fluoro-6-(trifluoromethyl)phenyl)methanamine; α-(Trifluoromethyl)-2-fluorobenzylamine; 1-(2-Fluoro-6-(trifluoromethyl)phenyl)methanamine; 2-Fluoro-α,α,α-trifluoro-o-toluidine; 2-Fluoro-6-trifluoromethylbenzylamine; Benzenemethanamine, 2-fluoro-α,α,α-trifluoro-; 2-Fluoro-α-(trifluoromethyl)benzylamine
EINECS	Contact for details

Quality Control

Every batch of 2-Fluoro-6-(Trifluoromethyl)Benzylamine is produced and tested under a strict quality management system to ensure consistency and reliability for your critical syntheses. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as purity, identity, and impurity profiles. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, and we support regulatory documentation needs for global markets including REACH and TSCA compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Individual impurity ≤ 0.5% Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.