Description

n-(2,2-Diethoxyethyl)-4-Fluoroaniline is a specialized aromatic amine derivative featuring both a protected aldehyde group (as a diethyl acetal) and a fluorine substituent. This unique bifunctional structure makes it a valuable versatile building block in advanced organic synthesis. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for constructing complex molecular architectures, particularly in the development of new active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, especially those requiring fluorinated aniline moieties for enhanced metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the fluorine atom can improve biological activity and environmental persistence.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Functional Material Research: Employed in the development of organic semiconductors, dyes, and photoactive materials due to its electron-donating aniline and modifiable acetal group.
• Custom Chemical Synthesis: A versatile scaffold for contract research organizations (CROs) and fine chemical manufacturers producing bespoke compounds for client projects.

Basic Information

Product Name	n-(2,2-Diethoxyethyl)-4-Fluoroaniline
CAS No.	239085-97-3
Molecular Formula	C₁₂H₁₈FNO₂
Molecular Weight	227.28 g/mol
Synonyms	4-Fluoro-N-(2,2-diethoxyethyl)aniline; 1-(2,2-Diethoxyethyl)-4-fluoroaniline; 4-Fluoroaniline, N-(2,2-diethoxyethyl)-; N-(2,2-Diethoxyethyl)-p-fluoroaniline; p-Fluoro-N-(2,2-diethoxyethyl)aniline; 2,2-Diethoxy-N-(4-fluorophenyl)ethan-1-amine; (2,2-Diethoxyethyl)(4-fluorophenyl)amine
EINECS	Contact for details

Quality Control

Our n-(2,2-Diethoxyethyl)-4-Fluoroaniline is produced under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, documenting all critical quality parameters. Our commitment to cGMP-compliant practices ensures reliability for research and scale-up applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The compound is light-sensitive (store away from light). Keep away from heat, sparks, and open flames. For long-term storage, consider an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.