Description

n-tert-Butyl-4-Fluoro-2-Nitroaniline is a specialized aromatic amine derivative, characterized by its tert-butyl and nitro-fluoro substitution pattern. This compound serves as a high-value pharmaceutical intermediate and organic synthesis building block, enabling the construction of complex molecules for advanced research and development. It is primarily required by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those targeting central nervous system (CNS) disorders or possessing specific receptor binding profiles.
• Agrochemical Synthesis: Building block for developing novel herbicides, fungicides, or plant growth regulators that leverage its aniline and nitro group chemistry.
• Dye and Pigment Manufacturing: Intermediate for producing specialized azo dyes and organic pigments where the fluorine and tert-butyl groups impart unique color fastness and solubility properties.
• Material Science Research: Used in the development of advanced polymers, liquid crystals, or organic electronic materials due to its aromatic structure and functional groups.
• Chemical Research & Development: Versatile reagent for academic and industrial research in organic synthesis, including palladium-catalyzed cross-coupling reactions and nucleophilic aromatic substitution.

Basic Information

Product Name	n-tert-Butyl-4-Fluoro-2-Nitroaniline
CAS No.	239080-03-6
Molecular Formula	C10H13FN2O2
Molecular Weight	212.22 g/mol
Synonyms	4-Fluoro-2-nitro-N-(tert-butyl)aniline; 1-tert-Butyl-4-fluoro-2-nitroaniline; N-(tert-Butyl)-4-fluoro-2-nitroaniline; 2-Nitro-4-fluoro-N-tert-butylaniline; Benzenamine, 4-fluoro-N-(1,1-dimethylethyl)-2-nitro-; tert-Butyl(4-fluoro-2-nitrophenyl)amine
EINECS	Contact for details

Quality Control

Our n-tert-Butyl-4-Fluoro-2-Nitroaniline is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing to ensure high purity and consistent performance. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay, identity, and impurity profiles. Our quality commitment aligns with cGMP principles where applicable, supporting its use in regulated synthesis pathways.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly sealed to prevent contamination and moisture absorption.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Individual impurity ≤ 0.5%, Total impurities ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.