Description

1-[4-(Trifluoromethyl)Pyrimidin-2-Yl]-1,4-Diazepane is a high-purity, heterocyclic organic compound featuring a diazepane core linked to a trifluoromethyl-substituted pyrimidine ring. This unique molecular architecture makes it a critical intermediate for the synthesis of novel active pharmaceutical ingredients (APIs) and agrochemicals, where the trifluoromethyl group is prized for enhancing metabolic stability and lipophilicity. It is primarily sought after by pharmaceutical R&D teams and fine chemical manufacturers engaged in developing next-generation therapeutics and crop protection agents.

Application

• Pharmaceutical Intermediate: A key building block in the research and synthesis of new drug candidates, particularly in oncology, CNS disorders, and antiviral therapies.
• Agrochemical Research: Used to develop advanced herbicides, fungicides, and insecticides, leveraging the bioactivity of the pyrimidine moiety.
• Chemical Biology Probe: Serves as a scaffold for creating molecular probes to study enzyme function and biological pathways.
• Material Science Precursor: Potential use in synthesizing specialty polymers and ligands for catalytic systems.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations providing custom synthesis and process development services.

Basic Information

Product Name	1-[4-(Trifluoromethyl)Pyrimidin-2-Yl]-1,4-Diazepane
CAS No.	238403-48-0
Molecular Formula	C10H13F3N4
Molecular Weight	246.24 g/mol
Synonyms	1,4-Diazepane, 1-[4-(trifluoromethyl)-2-pyrimidinyl]-; 1-(4-(Trifluoromethyl)pyrimidin-2-yl)-1,4-diazepane; 2-(1,4-Diazepan-1-yl)-4-(trifluoromethyl)pyrimidine; 238403-48-0; 1-(4-Trifluoromethyl-pyrimidin-2-yl)-[1,4]diazepane; 1-(4-(Trifluoromethyl)pyrimidin-2-yl)-1,4-diazepane
EINECS	Contact for details

Quality Control

Our 1-[4-(Trifluoromethyl)Pyrimidin-2-Yl]-1,4-Diazepane is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing including HPLC, NMR, and MS to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment supports compliance with cGMP and ISO standards for research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.