Description

3-Fluoro-4-Thiomorpholinoaniline is a specialized aromatic amine derivative featuring both fluorine and a thiomorpholine substituent. This compound serves as a high-value pharmaceutical intermediate and organic synthesis building block, prized for its unique structural motifs that enable the development of novel bioactive molecules. It is primarily utilized by research institutions and chemical manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors for creating new chemical entities.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Research: Building block for developing novel herbicides, fungicides, and insecticides, leveraging the fluorine and sulfur-containing heterocycle for enhanced bioactivity.
• Ligand and Catalyst Development: Used in organometallic chemistry to create novel ligands for transition metal catalysts used in cross-coupling and other synthetic transformations.
• Material Science: Intermediate for synthesizing functional polymers, dyes, and advanced organic electronic materials.
• Chemical Biology Probe Synthesis: Utilized in medicinal chemistry to create molecular probes for studying enzyme function and biological pathways.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific research and scale-up projects.

Basic Information

Product Name	3-Fluoro-4-Thiomorpholinoaniline
CAS No.	237432-11-0
Molecular Formula	C10H13FN2S
Molecular Weight	212.29 g/mol
Synonyms	4-(3-Fluoro-4-aminophenyl)thiomorpholine; 1-(3-Fluoro-4-aminophenyl)thiomorpholine; 3-Fluoro-4-(thiomorpholin-4-yl)aniline; Benzenamine, 3-fluoro-4-(4-thiomorpholinyl)-; 3-Fluoro-4-thiomorpholin-4-ylaniline; 4-(4-Amino-2-fluorophenyl)thiomorpholine; 3-Fluoro-4-(thiomorpholino)aniline; 237432-11-0
EINECS	Contact for details

Quality Control

Our 3-Fluoro-4-Thiomorpholinoaniline is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and Mass Spectrometry. We provide comprehensive Certificates of Analysis (COA) detailing all specifications, ensuring traceability and compliance with customer and research requirements. Our quality commitment supports applications in GMP-oriented synthesis where applicable.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This material is light-sensitive and should be handled under appropriate conditions to maintain stability. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	Off-white to light brown crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.