Description

Fmoc-Gly-Gly-Phe-Otbu is a protected tripeptide building block, specifically designed for solid-phase peptide synthesis (SPPS). This compound is essential for researchers and manufacturers requiring high-purity intermediates to construct complex peptides with precise sequences. It is primarily utilized in pharmaceutical R&D, biotechnology, and academic laboratories for the development of therapeutic peptides, diagnostic agents, and biochemical probes.

Application

• Solid-Phase Peptide Synthesis (SPPS): A key intermediate for the sequential assembly of custom peptide sequences.
• Pharmaceutical Research: Used in the discovery and development of novel peptide-based therapeutics and APIs.
• Bioconjugation: Serves as a linker or spacer molecule for attaching peptides to other biomolecules, surfaces, or carriers.
• Combinatorial Chemistry: Employed in libraries for high-throughput screening of bioactive peptide candidates.
• Biochemical Tool Development: Integral for creating enzyme substrates, inhibitors, or affinity ligands for proteomic studies.
• Academic & Contract Research: A fundamental reagent for synthetic chemistry and peptide science studies.

Basic Information

Product Name	Fmoc-Gly-Gly-Phe-Otbu
CAS No.	236426-37-2
Molecular Formula	C33H37N3O7
Molecular Weight	587.66 g/mol
Synonyms	Fmoc-Gly-Gly-Phe-OtBu; N-[(9H-Fluoren-9-ylmethoxy)carbonyl]glycylglycyl-L-phenylalanine tert-butyl ester; Fmoc-Gly-Gly-L-Phe-OtBu; Fmoc-Gly-Gly-Phe-O-tert-butyl; tert-Butyl N-[(9H-fluoren-9-ylmethoxy)carbonyl]glycylglycyl-L-phenylalaninate; Fmoc-Gly-Gly-Phe-OtBu (peptide synthesis building block); Fmoc-Gly-Gly-Phe-OtBu (SPPS reagent)
EINECS	Contact for details

Quality Control

Our Fmoc-Gly-Gly-Phe-Otbu is produced under stringent quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and chiral analysis to ensure stereochemical integrity. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to guarantee compliance with your research and production standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This material is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥98.0%
Specific Rotation	Contact for details
Water Content (KF)	≤1.0%
Heavy Metals	≤20 ppm
Residual Solvents	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.