Description

2,3,4-Trifluorobenzylamine is a versatile fluorinated aromatic amine building block of significant importance in advanced organic synthesis. Its value lies in the unique electronic and steric properties imparted by the trifluoromethylbenzyl motif, which is critical for modulating the biological activity and physicochemical characteristics of target molecules. This compound is primarily needed by research and development teams in the pharmaceutical and agrochemical industries for the creation of novel active ingredients, as well as by manufacturers of specialty chemicals and liquid crystals.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in candidates targeting the central nervous system, oncology, and anti-infective therapies.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the fluorine atoms enhance lipophilicity and metabolic stability.
• Liquid Crystal Materials: Serves as a building block for fluorinated liquid crystal compounds used in high-performance displays.
• Organic Light-Emitting Diodes (OLEDs): Employed in the synthesis of electron-transport or host materials for OLED devices.
• Polymer Modification: Acts as a functional monomer or cross-linking agent to introduce amine functionality into specialty polymers.
• Chemical Research & Development: A valuable reagent for medicinal chemistry, facilitating structure-activity relationship (SAR) studies and library synthesis.

Basic Information

Product Name	2,3,4-Trifluorobenzylamine
CAS No.	235088-67-2
Molecular Formula	C7H6F3N
Molecular Weight	161.12 g/mol
Synonyms	(2,3,4-Trifluorophenyl)methanamine; 1-(Aminomethyl)-2,3,4-trifluorobenzene; 2,3,4-Trifluorobenzyl amine; α-Amino-2,3,4-trifluorotoluene; Benzenemethanamine, 2,3,4-trifluoro-; 2,3,4-Trifluoro-α-toluidine
EINECS	Contact for details

Quality Control

Our 2,3,4-Trifluorobenzylamine is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. We provide comprehensive quality assurance, with products typically meeting specifications suitable for research and industrial synthesis. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available for every batch upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.