Description

Valine, n-Acetyl-n-Methyl- is a chemically modified derivative of the essential amino acid L-Valine, featuring both acetylation and methylation on the nitrogen atom. This specific modification is crucial for enhancing metabolic stability and membrane permeability, making it a valuable building block in advanced research and synthesis. It is primarily utilized by pharmaceutical researchers, peptide chemists, and fine chemical manufacturers developing novel therapeutic agents and biochemical tools.

Application

• Pharmaceutical Intermediate: Serves as a key synthon in the research and development of peptide-based drugs and prodrugs.
• Peptide Chemistry: Used in solid-phase and solution-phase peptide synthesis to introduce modified valine residues, altering the biological activity and stability of peptides.
• Biochemical Research: Employed as a standard or reagent in metabolic pathway studies and enzyme substrate research.
• Fine Chemical Synthesis: Acts as a specialized building block for synthesizing complex organic molecules and chiral compounds.
• Protecting Group Strategy: The acetyl and methyl groups can function as part of a protecting group scheme in multi-step organic syntheses.

Basic Information

Product Name	Valine, n-Acetyl-n-Methyl-
CAS No.	234772-49-7
Molecular Formula	C8H15NO3
Molecular Weight	173.21 g/mol
Synonyms	N-Acetyl-N-methyl-L-valine; N-Acetyl-N-methylvaline; (2S)-2-Acetamido-3-methyl-N-methylbutanamide; Ac-N-Me-Val-OH; N-ACETYL-N-METHYLVALINE; N-Acetyl-N-methyl-L-valine; N-Ac-N-Me-Val-OH; Modified Valine derivative
EINECS	Contact for details

Quality Control

Our Valine, n-Acetyl-n-Methyl- is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis, and identity confirmation via IR and NMR spectroscopy. A Certificate of Analysis (COA) detailing all specifications is provided to ensure traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); ensure the container is sealed after each use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Optical Rotation	Contact for details
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.