Description

cis-2-(9-Fluorenylmethoxycarbonylamino)Cyclohex-3-Enecarboxylic Acid is a sophisticated Fmoc-protected amino acid derivative, a critical building block in modern solid-phase peptide synthesis (SPPS). Its value lies in providing a protected, stereochemically defined amino acid component that enables the precise construction of complex peptides and peptidomimetics. This high-purity intermediate is essential for researchers and manufacturers in pharmaceutical development, biotechnology, and advanced materials science who require reliable, high-quality reagents for producing therapeutic peptides and bioactive compounds.

Application

• Solid-Phase Peptide Synthesis (SPPS): A key protected amino acid building block for the automated synthesis of custom peptides.
• Pharmaceutical Research & Development: Used in the discovery and production of novel peptide-based drug candidates and active pharmaceutical ingredients (APIs).
• Peptidomimetic Design: Incorporates a constrained cyclohexene ring, making it valuable for creating conformationally restricted analogs to enhance metabolic stability and receptor selectivity.
• Bioconjugation and Probe Development: Serves as a precursor for synthesizing labeled peptides for diagnostic assays, imaging, and biochemical studies.
• Combinatorial Chemistry Libraries: Employed to generate diverse peptide libraries for high-throughput screening against biological targets.
• Academic and Institutional Research: Supports fundamental studies in organic chemistry, medicinal chemistry, and chemical biology.

Basic Information

Product Name	cis-2-(9-Fluorenylmethoxycarbonylamino)Cyclohex-3-Enecarboxylic Acid
CAS No.	233600-20-9
Molecular Formula	C22H21NO4
Molecular Weight	363.41 g/mol
Synonyms	Fmoc-cis-2-amino-cyclohex-3-ene-1-carboxylic acid; (1S,2R,6S)-2-[[(9H-Fluoren-9-ylmethoxy)carbonyl]amino]bicyclo[4.1.0]hept-3-ene-1-carboxylic acid; Fmoc-Achc-OH (cis); Fmoc-2-amino-cyclohex-3-ene-1-carboxylic acid (cis); N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-cis-2-aminocyclohex-3-ene-1-carboxylic acid; (1S,2R,6S)-2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)bicyclo[4.1.0]hept-3-ene-1-carboxylic acid
EINECS	Contact for details

Quality Control

Our cis-2-(9-Fluorenylmethoxycarbonylamino)Cyclohex-3-Enecarboxylic Acid is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity, suitable for sensitive research and development applications. Each lot undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to guarantee compliance with your project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container should be kept sealed in a desiccated environment to prevent moisture uptake, which can affect stability and performance. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Specific Rotation	Contact for details
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.