Description

4-Trifluoromethyl-3-Fluorobenzyl Alcohol is a high-value fluorinated aromatic building block. This compound is critical for introducing trifluoromethyl and fluorobenzyl motifs into advanced molecular architectures, significantly altering physicochemical properties like lipophilicity and metabolic stability. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in oncology and central nervous system (CNS) drug discovery.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and insecticides where the trifluoromethyl group enhances biological activity.
• Liquid Crystal Materials: Serves as a precursor for fluorinated components in liquid crystal displays (LCDs) and organic light-emitting diodes (OLEDs).
• Polymer Chemistry: Employed to create specialty polymers and coatings with improved chemical resistance, thermal stability, and surface properties.
• Organic Synthesis & Catalysis: A versatile reagent in cross-coupling reactions and as a ligand precursor in organometallic catalysis.
• Material Science Research: Used in developing novel fluorinated materials for electronic and optical applications.

Basic Information

Product Name	4-Trifluoromethyl-3-Fluorobenzyl Alcohol
CAS No.	230295-16-6
Molecular Formula	C8H5F4O
Molecular Weight	193.12 g/mol
Synonyms	(3-Fluoro-4-(trifluoromethyl)phenyl)methanol; 3-Fluoro-α-(trifluoromethyl)benzenemethanol; 3-Fluoro-4-(trifluoromethyl)benzyl Alcohol; 1-(3-Fluoro-4-(trifluoromethyl)phenyl)methanol; α,α,α-Trifluoro-3-fluoro-p-tolylcarbinol
EINECS	Contact for details

Quality Control

Every batch of 4-Trifluoromethyl-3-Fluorobenzyl Alcohol is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, GC, NMR, and Karl Fischer titration, to ensure compliance with exacting purity and identity specifications. Certificates of Analysis (COA) detailing all test results are provided with each shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and degradation. Keep away from strong bases and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.