Description

2,3,6-Trifluorobenzylamine is a high-value fluorinated aromatic amine building block, essential for introducing the 2,3,6-trifluorobenzyl moiety into complex molecular architectures. Its unique substitution pattern offers significant advantages in modulating the lipophilicity, metabolic stability, and binding affinity of target compounds. This versatile intermediate is critically needed by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and oncology drug candidates.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and insecticides where the fluorine atoms enhance biological activity and environmental stability.
• Liquid Crystal & Electronic Materials: Serves as a precursor for fluorinated compounds used in liquid crystal displays (LCDs) and organic light-emitting diodes (OLEDs).
• Organic Synthesis & Catalysis: Employed as a ligand precursor or a specialized amine reagent in cross-coupling reactions and other catalytic processes.
• Material Science: Utilized in the creation of advanced polymers and coatings with specific thermal, chemical, or surface properties.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis projects and scale-up production under cGMP or ISO standards.

Basic Information

Product Name	2,3,6-Trifluorobenzylamine
CAS No.	230295-09-7
Molecular Formula	C7H6F3N
Molecular Weight	161.12 g/mol
Synonyms	(2,3,6-Trifluorophenyl)methanamine; 1-(Aminomethyl)-2,3,6-trifluorobenzene; 2,3,6-Trifluorobenzyl amine; α-Amino-2,3,6-trifluorotoluene; 2,3,6-Trifluorobenzenemethanamine; Benzenemethanamine, 2,3,6-trifluoro-
EINECS	Contact for details

Quality Control

Our 2,3,6-Trifluorobenzylamine is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay, identity, and impurity profiles. Our quality commitment aligns with cGMP and ISO guidelines where applicable, supporting its use in regulated synthesis pathways.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere (e.g., nitrogen) to prevent degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.