Description

Boc-L-β-Homotryptophan CAS NO 229639-48-9 is a protected, non-proteinogenic amino acid derivative of significant value in advanced organic synthesis and peptide research. This compound serves as a crucial chiral building block for constructing complex peptides with enhanced stability and specific biological activity. It is primarily utilized by pharmaceutical R&D teams, peptide synthesis specialists, and academic researchers focused on developing novel therapeutic agents and biochemical probes.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of novel peptide-based drugs and bioactive molecules.
• Peptide Synthesis: Used in solid-phase and solution-phase peptide synthesis (SPPS) to incorporate a modified tryptophan analog, expanding peptide libraries for structure-activity relationship (SAR) studies.
• Biochemical Research: Employed in the study of enzyme-substrate interactions, receptor binding, and the development of fluorescent or radiolabeled peptide tracers.
• Protecting Group Strategy: The tert-butoxycarbonyl (Boc) group provides orthogonal protection in multi-step synthetic sequences, allowing for selective deprotection under mild acidic conditions.
• Academic & Contract Research: Serves as a high-purity starting material for universities and CROs (Contract Research Organizations) engaged in medicinal chemistry and chemical biology projects.

Basic Information

Product Name	Boc-L-β-Homotryptophan
CAS No.	229639-48-9
Molecular Formula	C₁₇H₂₂N₂O₄
Molecular Weight	318.37 g/mol
Synonyms	(S)-2-((tert-Butoxycarbonyl)amino)-4-(1H-indol-3-yl)butanoic acid; Boc-β-homo-Trp-OH; N-Boc-L-β-Homotryptophan; N-(tert-Butoxycarbonyl)-L-β-homotryptophan; Boc-L-β-Homotryptophan; L-β-Homotryptophan, N-Boc-; 2-[[(1,1-Dimethylethoxy)carbonyl]amino]-4-(1H-indol-3-yl)butanoic acid; (S)-2-(tert-Butoxycarbonylamino)-4-(1H-indol-3-yl)butyric acid
EINECS	Contact for details

Quality Control

Our Boc-L-β-Homotryptophan is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis for enantiomeric excess, and spectroscopic identification. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to ensure traceability and compliance with your research and development requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This product is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% ee
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.