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H-Arg-Arg-Ala(2-Naphthyl)-Cys-Tyr-Arg-Lys-D-Lys-Pro-Tyr-Arg-Cit-Cys-Arg-Oh CAS NO 229030-20-0
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CAS No.:229030-20-0
Grade:Pharmacy Grade
Content:99.9%
Brand:Customizable
Packaging:Customizable
Description
H-Arg-Arg-Ala(2-Naphthyl)-Cys-Tyr-Arg-Lys-D-Lys-Pro-Tyr-Arg-Cit-Cys-Arg-Oh is a synthetic, chemically modified peptide sequence designed for advanced research and development. This compound is significant for its specific structural motifs, including D-amino acids and naphthylalanine, which confer unique stability and binding properties. It is primarily utilized by pharmaceutical and biotechnology R&D teams focused on novel therapeutic discovery, particularly in areas requiring protease-resistant or receptor-targeting peptide frameworks.
Application
- Pharmaceutical Research: Serves as a key intermediate or reference standard in the discovery and development of novel peptide-based therapeutics.
- Biochemical Assay Development: Used as a substrate or inhibitor in enzymatic studies, particularly for proteases, due to its engineered sequence.
- Structure-Activity Relationship (SAR) Studies: The incorporation of D-Lys and 2-Naphthyl-Ala allows researchers to investigate the impact of stereochemistry and aromatic bulk on biological activity and peptide stability.
- Diagnostic Reagent Component: Potential use in the development of specialized diagnostic kits and assays that require high-affinity, specific peptide ligands.
- Academic & Institutional Research: A valuable tool for universities and research institutes studying peptide chemistry, medicinal chemistry, and molecular biology.
Basic Information
| Product Name | H-Arg-Arg-Ala(2-Naphthyl)-Cys-Tyr-Arg-Lys-D-Lys-Pro-Tyr-Arg-Cit-Cys-Arg-Oh |
| CAS No. | 229030-20-0 |
| Molecular Formula | C99H157N39O19S2 |
| Molecular Weight | ~2230.68 g/mol |
| Synonyms | Arg-Arg-Ala(2-Naphthyl)-Cys-Tyr-Arg-Lys-D-Lys-Pro-Tyr-Arg-Cit-Cys-Arg; RRA(2-Nal)CYRK(k)DKYRCitCR-OH; Peptide RRA(2-Nal)CYRK(k)DKYRCitCR; H-Arg-Arg-Ala(2-Nal)-Cys-Tyr-Arg-Lys-D-Lys-Pro-Tyr-Arg-Cit-Cys-Arg-OH; Custom Peptide 229030-20-0; Research Peptide CAS 229030-20-0; Modified Arg-rich Peptide Sequence |
| EINECS | Contact for details |
Quality Control
Every batch of H-Arg-Arg-Ala(2-Naphthyl)-Cys-Tyr-Arg-Lys-D-Lys-Pro-Tyr-Arg-Cit-Cys-Arg-Oh is manufactured under strict quality management systems. Our products undergo rigorous quality testing, including advanced chromatographic and spectroscopic methods, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing purity (typically by HPLC), molecular weight confirmation (MS), and other critical parameters are available upon request to support your research and regulatory documentation needs.
Storage
Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dedicated freezer. This product is hygroscopic (moisture-sensitive); allow the sealed vial to equilibrate to room temperature before opening to minimize condensation and moisture uptake. For long-term storage, consider under an inert atmosphere.
Specification
| Item | Specification |
|---|---|
| Appearance | White to off-white lyophilized powder |
| Identification (HPLC & MS) | Conforms to reference standard |
| Purity (HPLC) | ≥ 95% |
| Single Impurity (HPLC) | ≤ 1.0% |
| Amino Acid Composition | Within ± 10% of theoretical |
| Peptide Content (UV) | ≥ 80% |
| Water Content (KF) | ≤ 5.0% |
Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.
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