Description

2-Bromo-4-Fluorobenzyl Alcohol is a versatile fluorinated and brominated benzyl alcohol derivative, serving as a critical building block in advanced organic synthesis. Its bifunctional halogenated structure makes it a valuable intermediate for constructing complex molecules with tailored electronic and steric properties. This compound is primarily utilized by research chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for applications ranging from drug discovery to specialty polymer synthesis.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules requiring halogenated aromatic motifs for bioactivity or metabolic stability.
• Agrochemical Synthesis: Building block for developing novel herbicides, fungicides, and insecticides where the bromo and fluoro substituents enhance lipophilicity and target binding.
• Liquid Crystal & OLED Materials: Used in the research and production of fluorinated liquid crystals and organic light-emitting diode (OLED) materials, where halogen atoms fine-tune electronic properties.
• Cross-Coupling Reactions: Serves as a substrate in palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Sonogashira) to create complex biaryl structures.
• Protecting Group Chemistry: The benzyl alcohol functionality can be used for protection/deprotection strategies in multi-step synthetic routes.
• Ligand & Catalyst Development: Intermediate for synthesizing specialized ligands and organocatalysts used in asymmetric synthesis.

Basic Information

Product Name	2-Bromo-4-Fluorobenzyl Alcohol
CAS No.	229027-89-8
Molecular Formula	C7H6BrFO
Molecular Weight	205.03 g/mol
Synonyms	(2-Bromo-4-fluorophenyl)methanol; 4-Fluoro-2-bromobenzyl alcohol; 2-Bromo-4-fluorobenzenemethanol; α-Hydroxymethyl-2-bromo-4-fluorobenzene; 1-Bromo-3-fluoro-4-(hydroxymethyl)benzene; 2-Bromo-4-fluoro-1-(hydroxymethyl)benzene; Benzenemethanol, 2-bromo-4-fluoro-
EINECS	Contact for details

Quality Control

Our 2-Bromo-4-Fluorobenzyl Alcohol is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, documenting all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliability for research and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, the container should be amber-colored or stored in a dark place.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Melting Point	Contact for details
Loss on Drying	≤0.5%
Related Substances (HPLC)	Total impurities ≤2.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.