Description

Pyrimidine, 5-[(2S)-2-Azetidinylmethoxy]- (9Ci) is a high-purity, advanced pharmaceutical intermediate featuring a unique azetidine-substituted pyrimidine scaffold. This compound is of significant value for medicinal chemistry research and development, particularly in the synthesis of novel therapeutic agents. It is primarily needed by pharmaceutical R&D laboratories and fine chemical manufacturers focused on developing new drug candidates, especially in areas like enzyme inhibition and targeted small-molecule therapies.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel active pharmaceutical ingredients (APIs) for preclinical and clinical development.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for new drug discovery programs.
• Enzyme Inhibitor Development: Serves as a core scaffold for designing potent and selective enzyme inhibitors due to its pyrimidine moiety.
• Chemical Biology Probes: Utilized in the development of molecular probes to study biological pathways and target validation.
• Custom Synthesis: Employed by contract research and manufacturing organizations (CROs/CMOs) for bespoke synthesis projects.
• Academic Research: Used in university and institutional labs for advanced organic synthesis and pharmacological studies.

Basic Information

Product Name	Pyrimidine, 5-[(2S)-2-Azetidinylmethoxy]- (9Ci)
CAS No.	228866-56-6
Molecular Formula	C8H11N3O
Molecular Weight	165.19 g/mol
Synonyms	5-[(2S)-2-Azetidinylmethoxy]pyrimidine; (S)-5-(Azetidin-2-ylmethoxy)pyrimidine; Azetidine, 2-[(5-pyrimidinyloxy)methyl]-, (2S)-; 228866-56-6; (S)-2-((Pyrimidin-5-yloxy)methyl)azetidine; 5-((S)-Azetidin-2-ylmethoxy)pyrimidine; 5-[(S)-2-Azetidinylmethoxy]pyrimidine
EINECS	Contact for details

Quality Control

Our Pyrimidine, 5-[(2S)-2-Azetidinylmethoxy]- (9Ci) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification, to ensure it meets the high standards required for pharmaceutical research. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (typically 15-25°C). This material is moisture-sensitive (hygroscopic); keep the container tightly sealed under an inert atmosphere if necessary to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥97.0%
Chiral Purity (Chiral HPLC)	≥98.0% ee
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.