Description

Glycine, n-3-Buten-1-Yl-n-[(9H-Fluoren-9-Ylmethoxy)Carbonyl]- is a specialized, protected amino acid derivative designed for advanced synthetic applications. This compound matters as a critical building block in solid-phase peptide synthesis (SPPS), where it enables the controlled and sequential assembly of complex peptide chains. It is primarily needed by research institutions and pharmaceutical companies engaged in the development of novel therapeutic peptides, peptidomimetics, and bioactive molecules. Its unique structure provides a reactive handle for further chemical elaboration while protecting sensitive functional groups during synthesis.

Application

• Solid-Phase Peptide Synthesis (SPPS): A key intermediate for the controlled, stepwise construction of custom peptide sequences.
• Pharmaceutical Research & Development: Used in the discovery and synthesis of novel peptide-based drug candidates and active pharmaceutical ingredients (APIs).
• Bioconjugation and Labeling: Serves as a linker or spacer molecule for attaching fluorophores, tags, or other functional groups to peptides.
• Combinatorial Chemistry Libraries: Employed in the generation of diverse compound libraries for high-throughput screening in drug discovery.
• Academic Research: Utilized in university and institutional labs for studying peptide structure, function, and synthesis methodologies.
• Production of Custom Peptides: A vital raw material for CROs and CDMOs offering bespoke peptide manufacturing services.

Basic Information

Product Name	Glycine, n-3-Buten-1-Yl-n-[(9H-Fluoren-9-Ylmethoxy)Carbonyl]-
CAS No.	227006-55-5
Molecular Formula	C22H23NO4
Molecular Weight	365.42 g/mol
Synonyms	Fmoc-But-3-enyl-glycine; N-(3-Buten-1-yl)-N-[(9H-fluoren-9-ylmethoxy)carbonyl]glycine; N-Fmoc-N-(but-3-en-1-yl)glycine; Fmoc-N-(but-3-enyl)glycine; (2-((((9H-Fluoren-9-yl)methoxy)carbonyl)(but-3-en-1-yl)amino)acetic acid); Glycine, N-(3-buten-1-yl)-N-[(9H-fluoren-9-ylmethoxy)carbonyl]-; Fmoc-Gly(But-3-enyl)-OH
EINECS	Contact for details

Quality Control

Our Glycine, n-3-Buten-1-Yl-n-[(9H-Fluoren-9-Ylmethoxy)Carbonyl]- is produced under strict quality management systems to ensure batch-to-batch consistency and high purity, suitable for sensitive research and development applications. Each lot undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation. Certificates of Analysis (COA) detailing all specifications and test results are provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to prevent degradation from atmospheric moisture. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.