Description

2-Methyl-Dl-Homophenylalanine is a non-natural amino acid derivative featuring a methyl group on the alpha carbon and an extended phenylalanine side chain. This structural modification makes it a valuable chiral building block and intermediate for the synthesis of more complex bioactive molecules. It is primarily utilized by research institutions and pharmaceutical companies engaged in peptide mimetic design, medicinal chemistry, and the development of novel therapeutic agents.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new active pharmaceutical ingredients (APIs), particularly for metabolic and neurological targets.
• Peptidomimetics & Constrained Peptides: Used to introduce steric hindrance and conformational constraints into peptide backbones, enhancing metabolic stability and bioavailability.
• Medicinal Chemistry & SAR Studies: Serves as a building block for creating analog libraries to explore structure-activity relationships in drug discovery programs.
• Biochemical Research: Employed in enzymatic studies and as a substrate analog to investigate enzyme mechanisms and inhibition.
• Organocatalyst & Ligand Synthesis: Acts as a precursor for the synthesis of novel chiral catalysts and ligands used in asymmetric synthesis.
• Reference Standard: Used as an analytical standard in quality control laboratories for method development and validation.

Basic Information

Product Name	2-Methyl-Dl-Homophenylalanine
CAS No.	225233-69-2
Molecular Formula	C11H15NO2
Molecular Weight	193.24 g/mol
Synonyms	DL-2-Methylhomophenylalanine; (±)-2-Amino-2-methyl-4-phenylbutanoic acid; 2-Amino-2-methyl-4-phenylbutyric acid; Hph(2Me)-OH; 2-Methyl-4-phenyl-2-aminobutanoic acid; α-Methylhomophenylalanine; 2-Methyl-DL-homo-Phe
EINECS	Contact for details

Quality Control

Our 2-Methyl-Dl-Homophenylalanine is manufactured under a quality management system and undergoes rigorous analytical testing to ensure batch-to-batch consistency and high purity. Standard quality parameters include chiral purity, chemical purity, and identification. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); keep the container tightly sealed to minimize exposure to atmospheric humidity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	DL-mixture (racemic)
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.