Description

N-(9-Fluorenylmethoxycarbonyl)-L-Alanine is a protected amino acid derivative essential for solid-phase peptide synthesis (SPPS). This compound serves as a critical building block, enabling the controlled and sequential assembly of complex peptides and proteins. It is primarily required by research institutions, pharmaceutical development labs, and fine chemical manufacturers engaged in the production of therapeutic peptides, diagnostic reagents, and biochemical research tools.

Application

• Solid-Phase Peptide Synthesis (SPPS): As an Fmoc-protected L-alanine derivative, it is a fundamental reagent for the stepwise construction of custom peptide sequences.
• Pharmaceutical Intermediates: Used in the research and development of novel peptide-based drugs, including hormones, antibiotics, and enzyme inhibitors.
• Bioconjugation: Acts as a linker or spacer molecule for attaching peptides to other biomolecules, surfaces, or carriers in bioconjugate chemistry.
• Combinatorial Chemistry: Employed in the generation of diverse peptide libraries for high-throughput screening in drug discovery.
• Biochemical Research: Utilized as a standard or substrate in enzymatic studies and proteomics research.
• Custom Peptide Service Providers: A key raw material for companies offering bespoke peptide synthesis services to the academic and industrial sectors.

Basic Information

Product Name	N-(9-Fluorenylmethoxycarbonyl)-L-Alanine
CAS No.	225101-67-7
Molecular Formula	C18H17NO4
Molecular Weight	311.33 g/mol
Synonyms	Fmoc-L-Alanine; Fmoc-Ala-OH; N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-L-alanine; (2S)-2-[(9H-Fluoren-9-ylmethoxy)carbonylamino]propanoic acid; N-α-Fmoc-L-alanine; L-Alanine, N-[(9H-fluoren-9-ylmethoxy)carbonyl]-; Fmoc-L-Ala-OH; Fmoc-Alanine
EINECS	Contact for details

Quality Control

Our N-(9-Fluorenylmethoxycarbonyl)-L-Alanine is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and chiral integrity, to ensure it meets the high standards required for peptide synthesis. Certificates of Analysis (COA) with detailed specifications are provided for every shipment, ensuring traceability and consistency for your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.5%
Optical Rotation	Contact for details
Chiral Purity (HPLC)	≥99.0%
Water Content (KF)	≤0.5%
Heavy Metals	≤10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.