Description

9H-Purine, 2-Chloro-9-[[3-(Cyclopentyloxy)-4-Methoxyphenyl]Methyl]-6,8-Dimethyl- is a high-purity, advanced pharmaceutical intermediate with a complex heterocyclic structure. This compound is critical for research and development in medicinal chemistry, particularly for its role as a key building block in the synthesis of novel therapeutic agents. It is primarily sought by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in developing new drug candidates, especially in oncology and immunology.

Application

• Pharmaceutical Intermediate: Serves as a crucial precursor in the multi-step synthesis of targeted small-molecule drugs.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for new therapeutic targets.
• Kinase Inhibitor Development: Acts as a core scaffold for the design and synthesis of potential kinase inhibitors due to its purine-based structure.
• Biochemical Research: Employed as a tool compound in biochemical assays to study enzyme function and cellular signaling pathways.
• Contract Manufacturing (CMO): Supplied to contract manufacturing organizations for the production of clinical trial materials and active pharmaceutical ingredients (APIs).
• Academic Research: Utilized in university and institutional labs for exploratory synthetic chemistry and drug discovery projects.

Basic Information

Product Name	9H-Purine, 2-Chloro-9-[[3-(Cyclopentyloxy)-4-Methoxyphenyl]Methyl]-6,8-Dimethyl-
CAS No.	225100-12-9
Molecular Formula	C₂₀H₂₃ClN₄O₂
Molecular Weight	386.87 g/mol
Synonyms	2-Chloro-9-[(3-cyclopentyloxy-4-methoxyphenyl)methyl]-6,8-dimethyl-9H-purine; 2-Chloro-9-[[3-(cyclopentyloxy)-4-methoxyphenyl]methyl]-6,8-dimethylpurine; 2-Chloro-6,8-dimethyl-9-[(3-cyclopentyloxy-4-methoxyphenyl)methyl]purine; 225100-12-9; 9H-Purine, 2-chloro-9-[[3-(cyclopentyloxy)-4-methoxyphenyl]methyl]-6,8-dimethyl-; 2-Chloro-9-((3-(cyclopentyloxy)-4-methoxybenzyl))-6,8-dimethyl-9H-purine
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to strict quality management systems, ensuring batch-to-batch consistency and high purity. Quality is verified through a comprehensive suite of analytical techniques including HPLC, GC, NMR, and mass spectrometry. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment. We support development and commercial projects with specifications that can meet the requirements of cGMP and ICH Q7 guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This compound is light-sensitive (store away from light) and may be hygroscopic (moisture-sensitive); therefore, containers should be kept tightly sealed under an inert atmosphere if specified. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.