Description

Methyl 3-Pyrimidin-5-Yl-Acrylate CAS NO 224776-14-1 is a high-purity, functionalized acrylate ester featuring a pyrimidine heterocycle. This compound is a critical pharmaceutical intermediate and building block for advanced organic synthesis. It is primarily utilized by R&D and production teams in the pharmaceutical, agrochemical, and specialty chemical industries for developing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of kinase inhibitors and other small-molecule drug candidates targeting various therapeutic areas.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and plant growth regulators.
• Material Science: Serves as a functional monomer for creating specialty polymers with tailored properties for coatings or advanced composites.
• Chemical Research: Employed in academic and industrial laboratories for heterocyclic chemistry, cross-coupling reactions, and the development of new synthetic methodologies.
• Ligand and Catalyst Development: The pyrimidine moiety can act as a coordinating group in the design of novel ligands and catalysts for asymmetric synthesis.

Basic Information

Product Name	Methyl 3-Pyrimidin-5-Yl-Acrylate
CAS No.	224776-14-1
Molecular Formula	C8H8N2O2
Molecular Weight	164.16 g/mol
Synonyms	Methyl (E)-3-(pyrimidin-5-yl)acrylate; (E)-Methyl 3-(pyrimidin-5-yl)acrylate; 5-Pyrimidineacrylic acid methyl ester; Methyl 3-(5-pyrimidinyl)-2-propenoate; 3-(Pyrimidin-5-yl)acrylic acid methyl ester; Propenoic acid, 3-(5-pyrimidinyl)-, methyl ester
EINECS	Contact for details

Quality Control

Our Methyl 3-Pyrimidin-5-Yl-Acrylate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation by NMR and IR spectroscopy, to ensure it meets the high standards required for research and production. Certificates of Analysis (COA) documenting all critical quality attributes are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (typically 15-25°C). The product may be sensitive to moisture and should be handled under inert atmosphere for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.