Description

N,N,n-Tri(Benzyloxycarbonyl) Deoxypyridinoline Tri-(tert-Butyl) Ester is a sophisticated, protected derivative of deoxypyridinoline, a key biomarker for bone resorption. This compound is essential as a high-purity chemical reference standard and synthetic intermediate in advanced pharmaceutical research and development. It is primarily utilized by pharmaceutical companies, contract research organizations (CROs), and diagnostic kit manufacturers for method development, calibration, and the synthesis of novel therapeutic agents targeting bone metabolism disorders.

Application

• Pharmaceutical Reference Standard: Critical for the quantitative analysis and validation of deoxypyridinoline levels in biological samples for osteoporosis and bone disease research.
• Advanced Intermediate Synthesis: Serves as a key protected building block in the multi-step synthesis of novel bone-targeting drugs and diagnostic probes.
• Biomarker Assay Development: Used in the development and calibration of immunoassays and chromatographic methods (HPLC, LC-MS/MS) for clinical diagnostics.
• Metabolic Pathway Studies: Employed in biochemical research to study collagen cross-link metabolism and bone turnover mechanisms.
• Quality Control Reagent: Acts as a purity standard for in-house quality control within pharmaceutical and diagnostic manufacturing.

Basic Information

Product Name	N,N,n-Tri(Benzyloxycarbonyl) Deoxypyridinoline Tri-(tert-Butyl) Ester
CAS No.	224629-59-8
Molecular Formula	C58H68N4O12
Molecular Weight	1013.19 g/mol
Synonyms	Deoxypyridinoline Tri-(tert-Butyl) Ester N,N,n-Tri-Cbz Derivative; Nτ,Nδ,n-Tri-Cbz-DPD Tri-(tert-Butyl) Ester; DPD Tri-(tert-Butyl) Ester Tri-Cbz; 5-Amino-3-({2-[(5-amino-5-carboxypentyl)amino]-2-oxoethyl}amino)-2,6-dioxo-1,2,3,6-tetrahydropyridine-1,3,5-tricarboxylic acid tris(1,1-dimethylethyl) ester Nτ,Nδ,n-tris(phenylmethyl) carbamate; Tris-Cbz Protected Deoxypyridinoline tert-Butyl Ester
EINECS	Contact for details

Quality Control

Our N,N,n-Tri(Benzyloxycarbonyl) Deoxypyridinoline Tri-(tert-Butyl) Ester is manufactured under strict quality systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and chiral purity checks where applicable, to ensure it meets the exacting standards for research and development. Certificates of Analysis (COA) with detailed chromatographic data are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a freezer at -20°C or below for long-term stability. The compound is sensitive to strong acids and organic solvents; ensure the container is kept in a cool, dry, and well-ventilated area. Allow the sealed container to equilibrate to room temperature before opening to prevent moisture condensation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.