Description

Dl-n-Fmoc-3-Pyrazol-1-Yl-Alanine is a specialized, non-natural amino acid derivative designed for advanced peptide synthesis and medicinal chemistry research. This compound is a critical building block for the solid-phase synthesis of peptides containing pyrazole-modified side chains, enabling the exploration of novel bioactive structures. It is primarily utilized by pharmaceutical R&D teams, biotech companies, and academic research institutions focused on developing peptide-based therapeutics, enzyme inhibitors, and chemical probes.

Application

• Solid-Phase Peptide Synthesis (SPPS): A key protected amino acid for the automated synthesis of peptides incorporating pyrazole functional groups.
• Medicinal Chemistry & Drug Discovery: Used to create peptide libraries for high-throughput screening and to develop novel enzyme inhibitors and receptor modulators.
• Bioconjugation & Chemical Biology: Serves as a versatile handle for site-specific labeling of peptides and proteins with fluorophores or other functional moieties.
• Proteomics Research: Employed in the synthesis of activity-based probes (ABPs) and affinity tags to study enzyme function and protein-protein interactions.
• Material Science: Can be used to synthesize functionalized peptides for creating bio-inspired materials and hydrogels.

Basic Information

Product Name	Dl-n-Fmoc-3-Pyrazol-1-Yl-Alanine
CAS No.	224173-50-6
Molecular Formula	C22H21N3O4
Molecular Weight	391.42 g/mol
Synonyms	Fmoc-DL-3-(1H-Pyrazol-1-yl)alanine; N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-3-(1H-pyrazol-1-yl)-DL-alanine; DL-Fmoc-3-(1-Pyrazolyl)alanine; Fmoc-3-(1-Pyrazolyl)-DL-alanine; 1H-Pyrazole-1-propanoic acid, α-[[(9H-fluoren-9-ylmethoxy)carbonyl]amino]-, (αR)-; N-Fmoc-3-(1-pyrazolyl)alanine; Fmoc-DL-3-(1-pyrazolyl)Ala-OH
EINECS	Contact for details

Quality Control

Our Dl-n-Fmoc-3-Pyrazol-1-Yl-Alanine is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and chiral analysis to verify the DL-mixture. We provide full traceability and Certificates of Analysis (COA) are available for all shipments, ensuring compliance with research and development standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.