Description

Bestatin (Trifluoroacetate) CAS NO 223763-80-2 is a high-purity trifluoroacetate salt form of the well-known aminopeptidase inhibitor, Bestatin. This specific salt form offers enhanced stability and solubility characteristics, making it a critical intermediate and reference standard in advanced pharmaceutical research and development. It is primarily utilized by researchers and manufacturers in the life sciences sector for biochemical studies, enzyme inhibition assays, and as a building block in the synthesis of novel therapeutic agents.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of novel drug candidates targeting aminopeptidases.
• Biochemical Research: Used as a potent and selective inhibitor of aminopeptidase N (APN/CD13) and leucine aminopeptidase in enzymatic studies.
• Reference Standard: Employed as a high-purity analytical standard for quality control and method validation in pharmaceutical analysis.
• Immunology & Cancer Research: Applied in studies investigating the role of aminopeptidases in immune modulation, angiogenesis, and tumor metastasis.
• Protease Inhibitor Cocktails: A component in specialized biochemical reagent kits for the stabilization of protein samples.
• Academic & Discovery Research: Utilized in university and institutional labs for fundamental research on enzyme mechanisms and inhibitor design.

Basic Information

Product Name	Bestatin (Trifluoroacetate)
CAS No.	223763-80-2
Molecular Formula	C16H24N2O4 • C2HF3O2
Molecular Weight	440.39 g/mol
Synonyms	Ubenimex Trifluoroacetate; (2S,3R)-3-Amino-2-hydroxy-4-phenylbutanoyl-L-leucine Trifluoroacetate; NK421 Trifluoroacetate; N-[(2S,3R)-3-Amino-2-hydroxy-4-phenylbutanoyl]-L-leucine Trifluoroacetate Salt; Bestatin TFA Salt; Aminopeptidase N Inhibitor (Trifluoroacetate); APN Inhibitor (Trifluoroacetate)
EINECS	Contact for details

Quality Control

Our Bestatin (Trifluoroacetate) is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis, and identity confirmation, to ensure it meets the stringent requirements for research and pharmaceutical applications. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting the specific results for that lot.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥98.0%
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.