Description

3-Amino-n-[(9H-Fluoren-9-Ylmethoxy)Carbonyl]- L-Phenylalanine is a specialized, high-purity amino acid derivative designed for advanced chemical synthesis. This compound is a critical building block in the production of complex peptides and active pharmaceutical ingredients (APIs), offering precise stereochemistry and functional group protection. It is essential for research and manufacturing in pharmaceutical development, biotechnology, and fine chemical synthesis, where reliable quality and structural integrity are paramount.

Application

• Solid-Phase Peptide Synthesis (SPPS): A key Fmoc-protected amino acid derivative for the controlled assembly of custom peptides.
• Pharmaceutical Intermediate: Serves as a crucial building block in the synthesis of novel therapeutic peptides and peptidomimetics.
• Bioconjugation and Labeling: Used to introduce specific functional handles or fluorescent tags into biomolecules for research and diagnostics.
• Combinatorial Chemistry: Employed in the generation of diverse chemical libraries for drug discovery and screening.
• Academic and R&D Laboratories: A fundamental reagent for studying peptide structure, function, and synthesis methodologies.
• Production of Custom Amino Acid Analogs: Acts as a starting material for the synthesis of non-natural amino acids with tailored properties.

Basic Information

Product Name	3-Amino-n-[(9H-Fluoren-9-Ylmethoxy)Carbonyl]- L-Phenylalanine
CAS No.	223581-75-7
Molecular Formula	C25H22N2O4
Molecular Weight	414.46 g/mol
Synonyms	Fmoc-3-Amino-L-phenylalanine; N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-3-amino-L-phenylalanine; Fmoc-3-Aph-OH; 3-Amino-L-phenylalanine, N-Fmoc derivative; (S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-3-(3-aminophenyl)propanoic acid; Fmoc-A3ph-OH; Fmoc-3-Amino-Phe-OH; Nα-Fmoc-3-amino-L-phenylalanine
EINECS	Contact for details

Quality Control

Our 3-Amino-n-[(9H-Fluoren-9-Ylmethoxy)Carbonyl]- L-Phenylalanine is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis, and identity confirmation, to ensure it meets the stringent requirements for pharmaceutical research and GMP-grade synthesis. A detailed Certificate of Analysis (COA) is provided with each shipment to guarantee traceability, consistency, and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation. For long-term storage, consider storage under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Optical Rotation	Contact for details
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.