Description

7H-Pyrazolo4,3-Dpyrimidin-7-One, 5-Amino-3-(2S,3S,4R,5R)-3,4-Dihydroxy-5-Methyl-2-Pyrrolidinyl-1,4-Dihydro- is a high-purity, complex heterocyclic compound featuring a fused pyrazolopyrimidine core with a stereochemically defined pyrrolidinyl substituent. This molecule is of significant interest in advanced pharmaceutical research and development, particularly as a sophisticated building block or potential intermediate for novel therapeutics. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, biotechnology, and fine chemical sectors.

Application

• Pharmaceutical Intermediate: Serves as a critical chiral building block in the synthesis of complex drug candidates, especially those targeting kinase inhibition or other enzyme-related pathways.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies and the development of new chemical entities (NCEs) with potential biological activity.
• Process Chemistry & Scale-Up: Employed in route scouting and optimization for the commercial-scale production of active pharmaceutical ingredients (APIs).
• Biochemical Tool Compound: May be utilized in biochemical assays to study specific biological mechanisms or as a reference standard.
• Fine Chemical Synthesis: Acts as a specialized precursor for synthesizing other high-value, complex organic molecules in custom synthesis projects.

Basic Information

Product Name	7H-Pyrazolo4,3-Dpyrimidin-7-One, 5-Amino-3-(2S,3S,4R,5R)-3,4-Dihydroxy-5-Methyl-2-Pyrrolidinyl-1,4-Dihydro-
CAS No.	222631-88-1
Molecular Formula	C12H16N6O3
Molecular Weight	292.30 g/mol
Synonyms	5-Amino-3-[(2S,3S,4R,5R)-3,4-dihydroxy-5-methylpyrrolidin-2-yl]-1,4-dihydro-7H-pyrazolo[4,3-d]pyrimidin-7-one; (2S,3S,4R,5R)-5-Amino-2-(3,4-dihydroxy-5-methylpyrrolidin-2-yl)-1,4-dihydro-7H-pyrazolo[4,3-d]pyrimidin-7-one; 5-Amino-3-((2S,3S,4R,5R)-3,4-dihydroxy-5-methylpyrrolidin-2-yl)-1,4-dihydro-7H-pyrazolo[4,3-d]pyrimidin-7-one; CAS 222631-88-1; 7H-Pyrazolo[4,3-d]pyrimidin-7-one, 5-amino-3-[(2S,3S,4R,5R)-3,4-dihydroxy-5-methyl-2-pyrrolidinyl]-1,4-dihydro-
EINECS	Contact for details

Quality Control

Our 7H-Pyrazolo4,3-Dpyrimidin-7-One, 5-Amino-3-(2S,3S,4R,5R)-3,4-Dihydroxy-5-Methyl-2-Pyrrolidinyl-1,4-Dihydro- is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification, to ensure it meets the high standards required for pharmaceutical research. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. For long-term storage, consider desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0%
Single Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.