Description

5H-Pyrrolo[3,2-d]pyrimidine, 2,4-Bis(phenylmethoxy)- is a high-purity, advanced pharmaceutical intermediate of significant commercial interest. This compound is valued for its role as a key synthetic building block in the development of novel active pharmaceutical ingredients (APIs). It is primarily utilized by research institutions and manufacturers in the pharmaceutical and biotechnology sectors engaged in drug discovery and process chemistry.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of complex heterocyclic compounds for potential therapeutic applications.
• Drug Discovery & Development: Used in medicinal chemistry research for constructing molecular scaffolds with targeted biological activity.
• Nucleoside Analogue Synthesis: Acts as a protected or modified base in the preparation of novel nucleoside analogues for antiviral or anticancer research.
• Kinase Inhibitor Research: Employed in the development of small molecule inhibitors targeting various kinase enzymes.
• Chemical Biology Probes: Utilized for creating specialized probes to study enzyme function and cellular pathways.
• Process Chemistry & Scale-up: Supplied for route scouting, optimization, and pilot-scale manufacturing of candidate drugs.

Basic Information

Product Name	5H-Pyrrolo[3,2-d]pyrimidine, 2,4-Bis(phenylmethoxy)-
CAS No.	222631-56-3
Molecular Formula	C20H18N2O2
Molecular Weight	318.37 g/mol
Synonyms	2,4-Bis(benzyloxy)-5H-pyrrolo[3,2-d]pyrimidine; 2,4-Di-O-benzyl-5H-pyrrolo[3,2-d]pyrimidine; 5H-Pyrrolo[3,2-d]pyrimidine, 2,4-bis(benzyloxy)-; 2,4-Bis(benzyloxy)pyrrolo[3,2-d]pyrimidine; 2,4-Dibenzyloxypyrrolo[3,2-d]pyrimidine
EINECS	Contact for details

Quality Control

Our 5H-Pyrrolo[3,2-d]pyrimidine, 2,4-Bis(phenylmethoxy)- is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for pharmaceutical R&D and manufacturing. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and physical characteristics is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (typically 15-25°C). Keep the container tightly sealed in a dry environment to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Individual impurity ≤ 0.5%
Total Impurities	≤ 2.0%
Residual Solvents (GC)	Complies with ICH guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.