Description

4H-Pyrrolo3,2-Dpyrimidin-4-One, 2-Amino-1,5-Dihydro-7-(2R,4S,5R)-4-Hydroxy-5-(Hydroxymethyl)-2-Pyrrolidinyl- is a high-purity, advanced pharmaceutical intermediate with a complex heterocyclic structure. This compound is critical for the synthesis of novel antiviral and anticancer agents, offering researchers and manufacturers a reliable building block for complex molecular architectures. It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in the development of nucleoside analog therapeutics.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of nucleoside analog drugs targeting viral infections and oncology.
• Antiviral Drug Research: Used in the development of novel therapeutic agents against a range of viral pathogens.
• Oncology Research: Serves as a precursor in the creation of experimental chemotherapeutic compounds.
• Biochemical Research: Employed in enzymatic studies and as a substrate analog in biochemical assays.
• Process Chemistry: Utilized in scale-up and optimization of synthetic routes for active pharmaceutical ingredients (APIs).
• Custom Synthesis: A starting material for the contract manufacturing of specialized, high-value fine chemicals.

Basic Information

Product Name	4H-Pyrrolo3,2-Dpyrimidin-4-One, 2-Amino-1,5-Dihydro-7-(2R,4S,5R)-4-Hydroxy-5-(Hydroxymethyl)-2-Pyrrolidinyl-
CAS No.	222631-33-6
Molecular Formula	C11H15N5O3
Molecular Weight	265.27 g/mol
Synonyms	2-Amino-7-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-1,5-dihydro-4H-pyrrolo[3,2-d]pyrimidin-4-one; 2-Amino-7-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl]-1,5-dihydro-4H-pyrrolo[3,2-d]pyrimidin-4-one; 7-((2R,4S,5R)-4-Hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-2-amino-4,5-dihydro-4H-pyrrolo[3,2-d]pyrimidin-4-one; A Modified Nucleoside Analog Intermediate; Pyrrolopyrimidine nucleoside derivative
EINECS	Contact for details

Quality Control

Our 4H-Pyrrolo3,2-Dpyrimidin-4-One derivative is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and chiral purity verification, to ensure it meets the exacting standards required for pharmaceutical research and development. Certificates of Analysis (COA) with detailed chromatographic data are available upon request, providing full traceability and compliance support for regulatory filings.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.