Description

2-Amino-4-Chloro-6,7-Dimethoxyquinazoline is a high-purity, advanced pharmaceutical intermediate with significant synthetic utility. This compound is valued for its role as a key building block in the development of targeted therapeutic agents, particularly kinase inhibitors. It is essential for research and development teams in the pharmaceutical, biotechnology, and fine chemical sectors seeking to develop novel drug candidates.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of small molecule kinase inhibitors for oncology and other therapeutic areas.
• Research & Development: Used in medicinal chemistry for structure-activity relationship (SAR) studies and lead optimization.
• Active Pharmaceutical Ingredient (API) Synthesis: Serves as a core scaffold in multi-step synthetic routes for potential drug substances.
• Biochemical Research: Employed as a tool compound in biochemical assays to study enzyme inhibition and cellular signaling pathways.
• Custom Synthesis: A starting material for the contract manufacturing of specialized and proprietary compounds.

Basic Information

Product Name	2-Amino-4-Chloro-6,7-Dimethoxyquinazoline
CAS No.	221698-39-1
Molecular Formula	C₁₁H₁₂ClN₃O₂
Molecular Weight	253.69 g/mol
Synonyms	4-Chloro-6,7-dimethoxyquinazolin-2-amine; 2-Amino-4-chloro-6,7-dimethoxyquinazoline; 6,7-Dimethoxy-2-amino-4-chloroquinazoline; 4-Chloro-2-amino-6,7-dimethoxyquinazoline; 221698-39-1; Quinazoline, 2-amino-4-chloro-6,7-dimethoxy-; AC6,7DMQ
EINECS	Contact for details

Quality Control

Our 2-Amino-4-Chloro-6,7-Dimethoxyquinazoline is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥98.0%
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm
Single Unknown Impurity (HPLC)	≤0.5%
Total Impurities (HPLC)	≤2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.