Description

5-Chloro-2-Fluoro-4-Methoxy-Benzaldehyde is a versatile fluorinated aromatic aldehyde building block of significant importance in advanced organic synthesis. Its molecular structure, featuring chloro, fluoro, and methoxy substituents, makes it a critical intermediate for constructing complex molecules with tailored electronic and steric properties. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, where it is used to develop novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules requiring a halogenated benzaldehyde core.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and insecticides, where the fluorine atom enhances biological activity and metabolic stability.
• Liquid Crystal & OLED Materials: Serves as a building block for fluorinated aromatic components in electronic display materials and organic light-emitting diodes.
• Functional Dye & Pigment Chemistry: Employed in the synthesis of specialized dyes and pigments where the substituents modify color and light-fastness properties.
• Cross-Coupling Reactions: The aldehyde and halogen groups make it a suitable substrate for Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions.
• Chemical Research & Development: A valuable reagent for academic and industrial R&D in medicinal chemistry and material science.

Basic Information

Product Name	5-Chloro-2-Fluoro-4-Methoxy-Benzaldehyde
CAS No.	221622-80-6
Molecular Formula	C8H6ClFO2
Molecular Weight	188.58 g/mol
Synonyms	4-Methoxy-5-chloro-2-fluorobenzaldehyde; 2-Fluoro-4-methoxy-5-chlorobenzaldehyde; 5-Chloro-2-fluoro-4-methoxybenzaldehyde; 5-Chloro-2-fluoro-4-methoxybenzenecarboxaldehyde; 2-Fluoro-5-chloro-4-methoxybenzaldehyde; Benzaldehyde, 5-chloro-2-fluoro-4-methoxy-; 221622-80-6
EINECS	Contact for details

Quality Control

Our 5-Chloro-2-Fluoro-4-Methoxy-Benzaldehyde is produced under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly sealed to prevent contamination and moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.