Description

4-Amino-1-tert-Butyl-3-(1'-Naphthyl)Pyrazolo[3,4-D]Pyrimidine is a high-purity, heterocyclic organic compound belonging to the pyrazolopyrimidine class, which serves as a critical advanced intermediate in pharmaceutical research and development. Its value lies in its role as a sophisticated building block for creating novel therapeutic agents, particularly kinase inhibitors targeting various disease pathways. This compound is essential for R&D chemists and process development scientists in the pharmaceutical, biotechnology, and fine chemical industries who require reliable, high-quality intermediates for drug discovery programs.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel kinase inhibitors for oncology and inflammatory disease research.
• Biochemical Research: Used as a reference standard or probe compound in enzymatic assays and target validation studies.
• Medicinal Chemistry: Serves as a core scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery.
• Fine Chemical Synthesis: Employed in the multi-step synthesis of complex, high-value specialty chemicals and active pharmaceutical ingredients (APIs).
• Academic Research: Utilized in university and institutional labs for developing new synthetic methodologies and exploring novel heterocyclic chemistry.

Basic Information

Product Name	4-Amino-1-tert-Butyl-3-(1'-Naphthyl)Pyrazolo[3,4-D]Pyrimidine
CAS No.	221243-82-9
Molecular Formula	C19H19N5
Molecular Weight	317.39 g/mol
Synonyms	1-(1,1-Dimethylethyl)-3-(1-naphthalenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine; 4-Amino-1-tert-butyl-3-(naphthalen-1-yl)-1H-pyrazolo[3,4-d]pyrimidine; 1H-Pyrazolo[3,4-d]pyrimidin-4-amine, 1-(1,1-dimethylethyl)-3-(1-naphthalenyl)-; 4-Amino-1-tert-butyl-3-(1-naphthyl)pyrazolo[3,4-d]pyrimidine; tert-Butyl 4-amino-3-(1-naphthyl)pyrazolo[3,4-d]pyrimidine-1-carboxylate (related protected form); Kinase Inhibitor Intermediate PP-121 related compound
EINECS	Contact for details

Quality Control

Our 4-Amino-1-tert-Butyl-3-(1'-Naphthyl)Pyrazolo[3,4-D]Pyrimidine is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the high standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and physical characteristics is provided with each shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms to reference spectrum
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.