Description

5-(2-Aminoethyl)Pyrimidine-2,4(1H,3H)-Dione is a specialized pyrimidine derivative featuring a reactive aminoethyl side chain, making it a valuable bifunctional building block in organic synthesis. This compound is critical for researchers and manufacturers requiring precise molecular scaffolds for developing novel active ingredients. It is primarily utilized in the pharmaceutical and agrochemical industries for the synthesis of nucleoside analogs, heterocyclic compounds, and other high-value intermediates.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel antiviral and anticancer nucleoside analogs.
• Agrochemical Research: Building block for developing new herbicides and plant growth regulators with pyrimidine cores.
• Bioconjugation Chemistry: The aminoethyl group enables coupling reactions for labeling probes or creating antibody-drug conjugates (ADCs).
• Chemical Biology: Used in the design and synthesis of enzyme inhibitors and molecular probes targeting nucleic acid interactions.
• Material Science: Serves as a monomer or cross-linker in the development of specialty polymers and functionalized surfaces.
• Academic & R&D: Fundamental research reagent for exploring new heterocyclic chemistry and reaction methodologies.

Basic Information

Product Name	5-(2-Aminoethyl)Pyrimidine-2,4(1H,3H)-Dione
CAS No.	221170-25-8
Molecular Formula	C6H9N3O2
Molecular Weight	155.16 g/mol
Synonyms	5-(2-Aminoethyl)uracil; 2,4(1H,3H)-Pyrimidinedione, 5-(2-aminoethyl)-; 5-(2-Aminoethyl)-2,4-dihydroxypyrimidine; 5-(2-Aminoethyl)dihydro-2,4(1H,3H)-pyrimidinedione; 5-(2-Aminoethyl)-2,4-pyrimidinediol; 5-(β-Aminoethyl)uracil; N-(2-Aminoethyl)barbituric acid derivative; Aminoethyluracil
EINECS	Contact for details

Quality Control

Our 5-(2-Aminoethyl)Pyrimidine-2,4(1H,3H)-Dione is produced under a strict quality management system. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.