Description

Cyclo[L-Alanyl-D-Alloisoleucyl-(3S,4S)-3-Hydroxy-4-Methyloctanoyl-L-Phenylalanyl] is a complex, synthetic cyclic pentapeptide of significant interest in advanced pharmaceutical research and development. This compound, with CAS number 221111-70-2, is valued for its intricate molecular architecture, which serves as a key structural motif for studying peptide conformation, stability, and biological activity. It is primarily utilized by research institutions and pharmaceutical companies engaged in the discovery of novel therapeutic agents, particularly in the fields of oncology, metabolic disorders, and antimicrobial research.

Application

• Pharmaceutical Intermediate: Serves as a critical building block or precursor in the synthesis of more complex peptide-based drug candidates.
• Biochemical Research: Used as a reference standard or probe in studies of peptide-protein interactions, enzyme inhibition, and receptor binding assays.
• Structure-Activity Relationship (SAR) Studies: Essential for investigating how specific structural modifications within a cyclic peptide framework influence potency and selectivity.
• Drug Discovery Platforms: Incorporated into combinatorial chemistry libraries for high-throughput screening against various biological targets.
• Academic Research: Employed in university and institutional labs for fundamental research in organic synthesis, peptide chemistry, and medicinal chemistry.

Basic Information

Product Name	Cyclo[L-Alanyl-D-Alloisoleucyl-(3S,4S)-3-Hydroxy-4-Methyloctanoyl-L-Phenylalanyl]
CAS No.	221111-70-2
Molecular Formula	C34H51N5O7
Molecular Weight	641.80 g/mol
Synonyms	Cyclo(L-Ala-D-aIle-(3S,4S)-3-Hydroxy-4-methyloctanoyl-L-Phe); Cyclic Pentapeptide 221111-70-2; L-Ala-D-aIle-Hmo-L-Phe Cyclic Peptide; Hmo-containing Cyclic Peptide; [Cyclo(Ala-aIle-Hmo-Phe)]; (3S,4S)-3-Hydroxy-4-methyloctanoic Acid Cyclic Tetradepsipeptide; Cyclo[Ala-aIle-(3S,4S)-Hmo-Phe]
EINECS	Contact for details

Quality Control

This high-purity peptide is manufactured under controlled GMP-like conditions suitable for research applications. Every batch undergoes comprehensive analytical characterization to ensure identity, purity, and consistency. Certificates of Analysis (COA) are provided, detailing results from HPLC, MS, and NMR analyses. We are committed to supplying material that meets the stringent requirements of pharmaceutical R&D, and specifications can be aligned with client-specific protocols.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dedicated freezer. This product is hygroscopic (moisture-sensitive). Allow the sealed vial to equilibrate to room temperature before opening to minimize condensation and moisture uptake. For long-term storage, consider under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95.0%
Assay	≥ 98.0% (on anhydrous basis)
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%
Single Impurity (HPLC)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.