Description

L-Proline, 3-Hydroxy-1-Methyl-, (3S)- (9Ci) CAS NO 220941-15-1 is a high-purity, non-proteinogenic amino acid derivative characterized by its unique stereochemistry and functional groups. This compound serves as a critical chiral building block and intermediate in advanced organic synthesis, enabling the construction of complex molecular architectures. It is essential for research and development in the pharmaceutical and agrochemical industries, where precise stereochemical control is paramount for creating bioactive molecules.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of novel drug candidates, particularly in protease inhibitor and peptidomimetic research.
• Agrochemical Synthesis: Used in the development of advanced, stereospecific pesticides and herbicides with enhanced efficacy and environmental profiles.
• Biochemical Research: Serves as a substrate or inhibitor in enzymatic studies and as a component in custom peptide synthesis for structure-activity relationship (SAR) studies.
• Asymmetric Catalysis: Employed as a precursor for chiral ligands or organocatalysts used in stereoselective chemical transformations.
• Nutraceutical & Cosmetic Ingredient: Potential use in high-value specialty formulations where modified amino acids contribute to product functionality.

Basic Information

Product Name	L-Proline, 3-Hydroxy-1-Methyl-, (3S)- (9Ci)
CAS No.	220941-15-1
Molecular Formula	C6H11NO3
Molecular Weight	145.16 g/mol
Synonyms	(2S,3S)-3-Hydroxy-1-methylpyrrolidine-2-carboxylic acid; (3S)-3-Hydroxy-1-methyl-L-proline; 3-Hydroxy-1-methyl-L-proline; 1-Methyl-3-hydroxy-L-proline; trans-3-Hydroxy-1-methyl-L-proline; (3S)-1-Methyl-3-hydroxyproline; L-1-Methyl-3-hydroxyproline; 220941-15-1
EINECS	Contact for details

Quality Control

Our L-Proline, 3-Hydroxy-1-Methyl-, (3S)- (9Ci) is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including chiral purity verification and impurity profiling by HPLC, to ensure it meets the stringent requirements for advanced synthetic applications. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming identity, purity, and compliance with agreed specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under dry, inert conditions to maintain stability and purity. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.