Description

tert-Butyl 4-Amino-2-Fluorophenylcarbamate is a high-purity, fluorinated aromatic building block of significant importance in advanced organic synthesis. This compound is valued for its role as a key protected intermediate in the development of active pharmaceutical ingredients (APIs) and other fine chemicals. It is primarily needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Synthesis: Used in the research and development of advanced pesticides and herbicides, where the fluorine atom and aniline moiety impart desirable biological activity and stability.
• Protecting Group Chemistry: The tert-butyloxycarbonyl (Boc) group serves as a temporary protecting group for amines, enabling selective multi-step synthetic sequences.
• Material Science Research: Employed as a monomer or precursor in the development of specialty polymers and advanced organic materials.
• Chemical Biology Probes: Useful in the design and synthesis of molecular probes and diagnostic agents for biochemical research.

Basic Information

Product Name	tert-Butyl 4-Amino-2-Fluorophenylcarbamate
CAS No.	220913-43-9
Molecular Formula	C11H15FN2O2
Molecular Weight	226.25 g/mol
Synonyms	2-Fluoro-4-aminophenyl tert-butylcarbamate; 4-Amino-2-fluorophenyl tert-butylcarbamate; tert-Butyl N-(4-amino-2-fluorophenyl)carbamate; 2-Fluoro-4-[(tert-butoxycarbonyl)amino]aniline; Boc-4-Amino-2-fluoroaniline; 4-[(tert-Butoxycarbonyl)amino]-2-fluoroaniline; 220913-43-9; 4-Amino-2-fluorophenylcarbamic acid tert-butyl ester
EINECS	Contact for details

Quality Control

Our tert-Butyl 4-Amino-2-Fluorophenylcarbamate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high chemical purity and identity. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to guarantee traceability and compliance with your research and production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥98.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm
Related Substances (HPLC)	Total impurities ≤2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.