Description

Benzenamine, n-Cyclopropyl-2-Fluoro- (9Ci) is a fluorinated aniline derivative featuring a cyclopropyl substituent, serving as a versatile and high-value synthetic building block. Its unique molecular architecture, combining an aromatic amine with fluorine and a strained cyclopropane ring, makes it a critical intermediate for constructing complex molecules with tailored properties. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical sectors for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of drug candidates, particularly those targeting central nervous system (CNS) disorders, infectious diseases, and oncology, where the fluorine atom and cyclopropyl group can enhance metabolic stability and binding affinity.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides, where its structure contributes to the efficacy and environmental profile of the final active ingredient.
• Material Science Research: Employed in the creation of specialty polymers, liquid crystals, or organic electronic materials that require specific fluorine-containing aromatic amines.
• Chemical Biology & Proteomics: Acts as a reactive handle or a component of chemical probes for studying biological systems and protein interactions.
• Organic Synthesis & Method Development: Serves as a challenging substrate for developing new fluorination, amination, or cross-coupling reactions in academic and industrial research laboratories.

Basic Information

Product Name	Benzenamine, n-Cyclopropyl-2-Fluoro- (9Ci)
CAS No.	220827-71-4
Molecular Formula	C9H10FN
Molecular Weight	151.18 g/mol
Synonyms	2-Fluoro-N-cyclopropylaniline; N-Cyclopropyl-2-fluoroaniline; 1-Cyclopropyl-2-fluorobenzeneamine; 2-Fluoro-N-cyclopropylbenzenamine; 2-Fluorocyclopropylaniline; (2-Fluorophenyl)(cyclopropyl)amine; FC6H4NHC3H5; 2-Fluoro-N-cyclopropyl-phenylamine
EINECS	Contact for details

Quality Control

Our production of Benzenamine, n-Cyclopropyl-2-Fluoro- (9Ci) adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity, essential for sensitive R&D and scale-up processes. Each lot is analyzed using advanced techniques including GC, HPLC, and NMR spectroscopy. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after initial opening to prevent degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Purity (HPLC/GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Individual impurity ≤ 1.0%; Total impurities ≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.