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L-Lysinamide, n-[(9H-Fluoren-9-Ylmethoxy)Carbonyl]-L-Alanyl-L-α-Glutamyl-L-Asparaginyl- (9Ci) CAS NO 220701-06-4


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CAS No.:220701-06-4

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

L-Lysinamide, n-[(9H-Fluoren-9-Ylmethoxy)Carbonyl]-L-Alanyl-L-α-Glutamyl-L-Asparaginyl- (9Ci) is a specialized, high-purity peptide derivative used as a critical building block in advanced biochemical synthesis. This compound matters for its role as a protected peptide intermediate, enabling the precise construction of complex peptide sequences for research and therapeutic development. It is primarily needed by pharmaceutical R&D laboratories, biotechnology companies, and academic institutions engaged in peptide chemistry, drug discovery, and proteomics research.

Application

  • Solid-Phase Peptide Synthesis (SPPS): A key protected intermediate for the sequential assembly of longer, biologically active peptide chains.
  • Pharmaceutical Research: Used in the discovery and development of novel peptide-based therapeutics, including hormone analogs and enzyme inhibitors.
  • Bioconjugation: Serves as a precursor for creating peptide-protein or peptide-small molecule conjugates for targeted drug delivery systems.
  • Biochemical Probe Development: Employed in the synthesis of labeled or modified peptides used as tools to study protein-protein interactions and cellular pathways.
  • Process Development & Scale-Up: Supports the optimization and manufacturing processes for peptide Active Pharmaceutical Ingredients (APIs).
  • Academic Research: A valuable reagent for graduate-level and post-doctoral studies in synthetic organic chemistry and medicinal chemistry.

Basic Information

Product Name L-Lysinamide, n-[(9H-Fluoren-9-Ylmethoxy)Carbonyl]-L-Alanyl-L-α-Glutamyl-L-Asparaginyl- (9Ci)
CAS No. 220701-06-4
Molecular Formula C37H48N8O11
Molecular Weight 780.83 g/mol
Synonyms Fmoc-Lys-Ala-Glu-Asp-NH2; Fmoc-KAED-NH2; Nα-Fmoc-L-lysyl-L-alanyl-L-α-glutamyl-L-asparaginamide; Fmoc-Lys(Ala,Glu,Asp)-NH2; (9H-Fluoren-9-ylmethoxy)carbonyl-L-lysyl-L-alanyl-L-α-glutamyl-L-asparaginamide; Fmoc-K(AED)-NH2; Protected KAED Tetrapeptide Amide; Fmoc-Lys-Ala-Glu-Asp-NH2
EINECS Contact for details

Quality Control

Our L-Lysinamide, n-[(9H-Fluoren-9-Ylmethoxy)Carbonyl]-L-Alanyl-L-α-Glutamyl-L-Asparaginyl- (9Ci) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical research. Certificates of Analysis (COA) with detailed chromatographic data are provided with every shipment to guarantee traceability, consistency, and reliability for your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a freezer. This product is hygroscopic (moisture-sensitive) and should be allowed to equilibrate to room temperature in a desiccator before opening to prevent condensation and hydrolysis. For long-term stability, store under an inert atmosphere.

Specification

Item Specification
Appearance White to off-white powder
Identification (HPLC) Conforms
Identification (MS) Conforms
Purity (HPLC) ≥ 95.0%
Assay (HPLC) ≥ 98.0%
Water Content (KF) ≤ 5.0%
Single Impurity (HPLC) ≤ 1.0%
Heavy Metals ≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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Each batch undergoes strict QC, accompanied by COA, MSDS, and full compliance with international standards.

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