Description

Cyclopropanamine, 2-(4-Fluorophenyl)-, (1R,2S)- (9Ci) is a chiral cyclopropylamine derivative of significant interest in advanced organic synthesis. This compound serves as a critical, high-value building block for the development of novel active pharmaceutical ingredients (APIs) and fine chemicals. It is primarily sought after by research institutions and pharmaceutical companies engaged in the discovery and process development of new therapeutic agents, particularly those targeting central nervous system (CNS) disorders and other specialized applications.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and synthesis of novel drug candidates, especially in medicinal chemistry programs.
• Active Pharmaceutical Ingredient (API) Development: Used as a core structural motif in the construction of complex molecules with potential biological activity.
• Asymmetric Synthesis: Employed as a chiral amine auxiliary or building block in stereoselective chemical reactions to introduce the cyclopropane moiety.
• Biochemical Research: Utilized in the study of enzyme inhibitors and receptor ligands due to its constrained three-membered ring structure and fluorinated aromatic group.
• Fine Chemical Production: Serves as a precursor for the manufacture of specialized agrochemicals and advanced materials.
• Process Chemistry & Scale-up: Critical for optimizing synthetic routes from laboratory to pilot and commercial scale production of target molecules.

Basic Information

Product Name	Cyclopropanamine, 2-(4-Fluorophenyl)-, (1R,2S)- (9Ci)
CAS No.	220349-80-4
Molecular Formula	C9H10FN
Molecular Weight	151.18 g/mol
Synonyms	(1R,2S)-2-(4-Fluorophenyl)cyclopropanamine; (1R,2S)-rel-2-(4-Fluorophenyl)cyclopropanamine; (1R,2S)-2-(p-Fluorophenyl)cyclopropylamine; trans-2-(4-Fluorophenyl)cyclopropanamine; 2-(4-Fluorophenyl)cyclopropanamine (racemic mixture related); 4-Fluoro-trans-2-phenylcyclopropylamine; FC-Ph-cyclopropylamine
EINECS	Contact for details

Quality Control

Our production of Cyclopropanamine, 2-(4-Fluorophenyl)-, (1R,2S)- (9Ci) adheres to stringent quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity analysis by HPLC, to ensure compliance with exacting research and development standards. Certificates of Analysis (COA) detailing identity, purity, enantiomeric excess, and impurity profiles are provided and can be tailored to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.