Description

Fmoc-1-Aminomethyl-Cyclohexane Carboxylic Acid is a high-purity, protected amino acid derivative essential for advanced peptide synthesis. This compound serves as a critical building block, enabling the precise construction of complex peptide chains with enhanced stability and controlled reactivity. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel therapeutic peptides, peptidomimetics, and bioactive molecules.

Application

• Solid-Phase Peptide Synthesis (SPPS): A key Fmoc-protected amino acid for the automated, stepwise assembly of peptides.
• Peptidomimetic Drug Discovery: Incorporation of the rigid cyclohexane scaffold to create metabolically stable analogs of natural peptides.
• Combinatorial Chemistry Libraries: Used to generate diverse arrays of compounds for high-throughput screening against biological targets.
• Bioconjugation and Linker Chemistry: Serves as a versatile spacer or functional handle for attaching peptides to surfaces, carriers, or other molecules.
• Academic and Industrial Research: Fundamental reagent for studying protein-protein interactions, enzyme substrates, and receptor ligands.
• Production of Custom Peptides: Essential for contract research organizations (CROs) and CDMOs manufacturing peptides for clinical and commercial use.

Basic Information

Product Name	Fmoc-1-Aminomethyl-Cyclohexane Carboxylic Acid
CAS No.	220145-22-2
Molecular Formula	C₂₂H₂₃NO₄
Molecular Weight	365.42 g/mol
Synonyms	Fmoc-Amc-OH; N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-1-(aminomethyl)cyclohexanecarboxylic Acid; 1-[[(9H-Fluoren-9-ylmethoxy)carbonyl]aminomethyl]cyclohexanecarboxylic Acid; Fmoc-1-Amc-OH; Fmoc-Aminomethyl-cyclohexanecarboxylic Acid; (1-(((9H-Fluoren-9-ylmethoxy)carbonyl)aminomethyl)cyclohexane-1-carboxylic acid; Fmoc-Cyc(Acm)-OH
EINECS	Contact for details

Quality Control

Our Fmoc-1-Aminomethyl-Cyclohexane Carboxylic Acid is manufactured under strict quality systems to ensure batch-to-batch consistency and high purity, suitable for sensitive research and development applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant industry standards and can support requirements for cGMP manufacturing upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This material is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccant or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Purity (HPLC)	≥97.0%
Water Content (KF)	≤1.0%
Heavy Metals	≤20 ppm
Residue on Ignition	≤0.5%
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.