Description

2-Amino-5-Guanidinopentanoic Acid Hydrochloride is a high-purity, chemically defined derivative of arginine, a fundamental amino acid. This compound is critical for research and development in life sciences, serving as a key building block and reference standard. It is primarily utilized by pharmaceutical researchers, biochemical manufacturers, and academic institutions engaged in peptide synthesis, metabolic studies, and enzyme research.

Application

• Pharmaceutical Intermediate: A key chiral building block for the synthesis of novel peptide-based therapeutics and active pharmaceutical ingredients (APIs).
• Biochemical Research: Used as a substrate or inhibitor in enzymatic studies, particularly those involving arginase, nitric oxide synthase, and other enzymes in the urea cycle.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method validation in pharmaceutical and nutritional analysis.
• Peptide Synthesis: An essential protected arginine derivative for solid-phase and solution-phase peptide synthesis (SPPS), enabling the creation of complex polypeptides.
• Cell Culture Media: A component in specialized cell culture formulations and serum-free media for biotechnology and cell therapy applications.
• Nutritional Science: Used in research focused on amino acid metabolism, sports nutrition, and the development of specialized enteral/parenteral formulas.

Basic Information

Product Name	2-Amino-5-Guanidinopentanoic Acid Hydrochloride
CAS No.	220144-84-3
Molecular Formula	C6H15N5O2 • HCl
Molecular Weight	233.67 g/mol (Free base: 189.21 g/mol)
Synonyms	L-Arginine Hydrochloride (common commercial form); (S)-2-Amino-5-guanidinopentanoic acid hydrochloride; Arg-HCl; H-Arg-OH • HCl; NG,NG'-Dimethylarginine hydrochloride precursor; Guanidino-norvaline hydrochloride derivative; Amino acid derivative HCl salt
EINECS	Contact for details

Quality Control

Our 2-Amino-5-Guanidinopentanoic Acid Hydrochloride is manufactured under strict quality management systems. Each batch is subjected to comprehensive analytical testing, including HPLC for purity, chiral analysis for enantiomeric excess, and tests for residual solvents and heavy metals. We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with relevant standards for research and pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); the container must be kept tightly sealed in a dry environment to prevent absorption of atmospheric moisture, which can affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Optical Rotation	[α]D20: +21.0° to +23.0° (c=1 in H2O)
Chiral Purity (HPLC)	≥ 99.0% (L-Isomer)
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.