Description

3,5-Difluorobenzyl Chloride is a versatile and reactive organofluorine building block, primarily used as a key intermediate in advanced organic synthesis. Its value lies in the strategic introduction of fluorine atoms and a benzyl chloride functional group, enabling the construction of complex molecules with tailored properties. This compound is essential for R&D and production chemists in the pharmaceutical, agrochemical, and material science industries, where it serves as a precursor for active ingredients and specialty chemicals.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in the development of fluorine-containing drugs where the difluoro motif can enhance metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and pesticides, leveraging the fluorine atoms to improve efficacy and environmental profile.
• Liquid Crystal & OLED Materials: Serves as a precursor in the manufacture of fluorinated aromatic compounds for electronic display materials and organic light-emitting diodes (OLEDs).
• Polymer & Resin Modifier: Incorporated into polymer chains to alter physical properties such as thermal stability, chemical resistance, and surface characteristics.
• Cross-coupling Reactions: Utilized in palladium-catalyzed reactions (e.g., Suzuki, Heck) to create complex biaryl structures common in many advanced materials.
• Chemical Research & Development: A valuable reagent for exploring new synthetic methodologies and creating novel fluorinated compounds in academic and industrial labs.

Basic Information

Product Name	3,5-Difluorobenzyl Chloride
CAS No.	220141-71-9
Molecular Formula	C7H5ClF2
Molecular Weight	162.56 g/mol
Synonyms	1-(Chloromethyl)-3,5-difluorobenzene; (3,5-Difluorophenyl)methyl Chloride; α-Chloro-3,5-difluorotoluene; 3,5-Difluorobenzylchloride; 3,5-Difluoro(phenylmethyl) Chloride; 3,5-DFBC
EINECS	Contact for details

Quality Control

Our 3,5-Difluorobenzyl Chloride is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing to ensure high purity and consistency. Certificates of Analysis (COA) documenting identity, assay, and impurity profiles are provided with each shipment. We support compliance with relevant regulatory frameworks for industrial and research use.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent decomposition. Keep away from strong bases and incompatible materials.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.