Description

4(1H)-Quinazolinone, 2-(4-Azidophenyl)-8-Methoxy- (9Ci) is a specialized heterocyclic organic compound featuring a quinazolinone core functionalized with an azidophenyl group. This unique molecular architecture makes it a valuable photoaffinity labeling agent and a versatile building block for chemical biology and pharmaceutical research. It is primarily utilized by R&D chemists and scientists in the life sciences sector for developing novel probes and studying biological interactions.

Application

• Photoaffinity Labeling (PAL): A critical tool in chemical biology for covalently capturing and identifying transient protein-ligand interactions or mapping binding sites.
• Proteomics Research: Used to synthesize activity-based probes (ABPs) for profiling enzyme families and understanding disease mechanisms.
• Medicinal Chemistry: Serves as a key synthetic intermediate in the discovery and development of new drug candidates, particularly kinase inhibitors.
• Bioconjugation: The azide group allows for efficient "click chemistry" reactions, enabling the attachment of fluorophores, biotin, or other tags to biomolecules.
• Material Science: Potential use in the synthesis of advanced polymers or functional surfaces with light-responsive properties.

Basic Information

Product Name	4(1H)-Quinazolinone, 2-(4-Azidophenyl)-8-Methoxy- (9Ci)
CAS No.	220115-24-2
Molecular Formula	C15H11N5O2
Molecular Weight	293.28 g/mol
Synonyms	2-(4-Azidophenyl)-8-methoxy-4(1H)-quinazolinone; 8-Methoxy-2-(4-azidophenyl)-4(1H)-quinazolinone; 2-(4-Azidophenyl)-8-methoxyquinazolin-4(1H)-one; 220115-24-2; 4(1H)-Quinazolinone, 2-(4-azidophenyl)-8-methoxy-; 2-(4-Azidophenyl)-8-methoxy-1,4-dihydroquinazolin-4-one
EINECS	Contact for details

Quality Control

Our high-purity research chemicals are produced under strict quality management protocols. Each batch undergoes comprehensive analytical characterization, including HPLC for purity verification and spectroscopic methods (NMR, MS) for structural confirmation. A detailed Certificate of Analysis (COA) is provided with every shipment, ensuring traceability and compliance with your research specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is light-sensitive and should be handled under appropriate conditions to maintain stability. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	Off-white to light yellow powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95% (Area %)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.