Description

2-Amino-5-(Trifluoromethyl)Benzyl Alcohol is a high-value, multi-functional aromatic building block characterized by its amino and trifluoromethyl substituents. This compound matters for its role in introducing both basicity and lipophilicity into target molecules, which is critical for modulating the pharmacokinetic properties of advanced materials and active pharmaceutical ingredients. It is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for applications in medicinal chemistry and material science.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel drug candidates, particularly in kinase inhibitor and central nervous system (CNS) active compound libraries.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the trifluoromethyl group enhances biological activity and environmental stability.
• Liquid Crystal & OLED Materials: Serves as a precursor for functionalized aromatic cores in electronic materials, contributing to improved charge transport and thermal stability.
• Complex Ligand Synthesis: Employed in the preparation of specialized ligands for catalysis and metal-organic frameworks (MOFs).
• Fluorine Chemistry Research: An important substrate for studying structure-activity relationships (SAR) and introducing fluorine motifs into complex molecules.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects requiring this specific benzyl alcohol derivative.

Basic Information

Product Name	2-Amino-5-(Trifluoromethyl)Benzyl Alcohol
CAS No.	220107-65-3
Molecular Formula	C8H8F3NO
Molecular Weight	191.15 g/mol
Synonyms	2-Amino-α-(trifluoromethyl)benzenemethanol; (2-Amino-5-(trifluoromethyl)phenyl)methanol; 5-(Trifluoromethyl)anthranilyl alcohol; 2-Amino-5-trifluoromethylbenzyl alcohol; Benzenemethanol, 2-amino-α-(trifluoromethyl)-; α-(Trifluoromethyl)-2-aminobenzyl alcohol
EINECS	Contact for details

Quality Control

Our 2-Amino-5-(Trifluoromethyl)Benzyl Alcohol is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay, impurity profile, and physical characteristics. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliable supply for your critical R&D and scale-up projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is light-sensitive (store away from light). Keep away from strong oxidizing agents and acids. For long-term storage, consider an inert atmosphere to preserve stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (HPLC Area %)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.