Description

4-Bromo-D-Tryptophan is a halogenated derivative of the essential amino acid tryptophan, featuring a bromine atom at the 4-position of the indole ring. This specific stereochemistry and substitution pattern make it a valuable non-natural amino acid and a critical chiral building block for advanced research and synthesis. It is essential for scientists and manufacturers in the pharmaceutical and biotechnology sectors who require high-purity, structurally defined intermediates. The compound is supplied with full analytical documentation to ensure research integrity and process reliability.

Application

• Pharmaceutical Intermediate: A key chiral precursor in the synthesis of novel therapeutic agents, including peptide-based drugs and enzyme inhibitors.
• Biochemical Research: Used in proteomics and metabolic pathway studies to investigate protein structure, function, and interactions.
• Peptide Synthesis: Incorporated into custom peptides to modulate their biological activity, stability, and binding properties.
• Probe and Label Development: Serves as a starting material for creating fluorescent or affinity probes for cellular imaging and diagnostic applications.
• Medicinal Chemistry: Employed in structure-activity relationship (SAR) studies to explore new chemical entities for drug discovery programs.
• Reference Standard: Used as a high-purity analytical standard for quality control and method validation in analytical laboratories.

Basic Information

Product Name	4-Bromo-D-Tryptophan
CAS No.	219943-61-0
Molecular Formula	C11H11BrN2O2
Molecular Weight	283.12 g/mol
Synonyms	(2R)-2-Amino-3-(4-bromo-1H-indol-3-yl)propanoic acid; D-4-Bromotryptophan; (R)-4-Bromotryptophan; 4-Bromo-D-Trp; 4-Br-D-Trp-OH; 4-Bromo-DL-Tryptophan (isomeric mixture); 4-Bromotryptophan, D- isomer; BRN 8294346
EINECS	Contact for details

Quality Control

Every batch of 4-Bromo-D-Tryptophan is manufactured under strict quality management systems. Our products undergo rigorous quality testing, including chiral purity analysis, to ensure compliance with exacting research and development standards. A comprehensive Certificate of Analysis (COA), detailing identity, purity, and impurity profiles, is provided with each shipment to guarantee traceability and support your regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% (D-isomer)
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.