Description

4-Cyano-2-Fluorobenzyl Alcohol is a versatile and high-value fluorinated aromatic building block, essential for advanced organic synthesis. Its molecular structure, featuring both cyano and fluorobenzyl alcohol functional groups, makes it a critical intermediate for constructing complex molecules with tailored properties. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for applications in medicinal chemistry and crop protection.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides, where the fluorine atom enhances biological activity and metabolic stability.
• Liquid Crystal Materials: Serves as a building block for fluorinated liquid crystals used in advanced display technologies.
• Polymer Chemistry: Intermediate for creating specialty polymers and functional materials with specific optical or electronic properties.
• Organic Synthesis Reagent: A versatile reagent for introducing fluorobenzyl and cyano-substituted motifs into more complex molecular architectures.
• Chemical Research & Development: Fundamental compound for method development and exploration of new chemical spaces in academic and industrial R&D labs.

Basic Information

Product Name	4-Cyano-2-Fluorobenzyl Alcohol
CAS No.	219873-06-0
Molecular Formula	C8H6FNO
Molecular Weight	151.14 g/mol
Synonyms	2-Fluoro-4-(hydroxymethyl)benzonitrile; (2-Fluoro-4-cyanophenyl)methanol; 4-Cyano-2-fluorobenzyl alcohol; 2-Fluoro-4-cyanobenzyl alcohol; 4-(Hydroxymethyl)-3-fluorobenzonitrile; α-Hydroxy-2-fluoro-4-cyanotoluene; 2-Fluoro-α-hydroxy-p-tolunitrile; Benzonitrile, 2-fluoro-4-(hydroxymethyl)-
EINECS	Contact for details

Quality Control

Our 4-Cyano-2-Fluorobenzyl Alcohol is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and FTIR, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specifications and test results. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your most critical synthesis projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, containers must be kept tightly sealed to exclude moisture. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (GC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.