Description

4-Chloro-5-Methoxy-2-(Trifluoromethyl)Quinazoline is a high-value, multi-functional heterocyclic building block essential for advanced organic synthesis. Its unique molecular architecture, featuring a halogenated quinazoline core with methoxy and trifluoromethyl substituents, makes it a critical intermediate for developing novel active compounds. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for creating new drug candidates and crop protection agents with enhanced properties.

Application

• Pharmaceutical Intermediate: A key synthon for the development of kinase inhibitors, anticancer agents, and other biologically active small molecule therapeutics.
• Agrochemical Research: Used in the synthesis of novel herbicides, fungicides, and insecticides, leveraging the stability imparted by the trifluoromethyl group.
• Material Science Precursor: Serves as a building block for advanced organic electronic materials and functional dyes.
• Chemical Biology Probe: Utilized in medicinal chemistry for structure-activity relationship (SAR) studies and target identification.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs and research institutions for bespoke synthetic routes and scale-up projects.

Basic Information

Product Name	4-Chloro-5-Methoxy-2-(Trifluoromethyl)Quinazoline
CAS No.	219773-96-3
Molecular Formula	C₁₀H₆ClF₃N₂O
Molecular Weight	262.61 g/mol
Synonyms	4-Chloro-5-methoxy-2-(trifluoromethyl)quinazoline; 2-(Trifluoromethyl)-4-chloro-5-methoxyquinazoline; 5-Methoxy-4-chloro-2-trifluoromethylquinazoline; Quinazoline, 4-chloro-5-methoxy-2-(trifluoromethyl)-; 219773-96-3; 4-Chloro-5-methoxy-2-trifluoromethyl-quinazoline
EINECS	Contact for details

Quality Control

We supply 4-Chloro-5-Methoxy-2-(Trifluoromethyl)Quinazoline in high-purity grades suitable for research and development. Our products undergo rigorous quality testing to ensure batch-to-batch consistency and compliance with industry standards. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from incompatible materials such as strong bases and reducing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.