Description

Zabofloxacin CAS NO 219680-11-2 is a novel broad-spectrum fluoroquinolone antibiotic developed for its potent activity against respiratory pathogens, including drug-resistant strains. Its primary value lies in its enhanced efficacy against quinolone-resistant bacteria, offering a critical therapeutic option in the global fight against antimicrobial resistance. This advanced pharmaceutical intermediate is essential for research institutions, contract development and manufacturing organizations (CDMOs), and pharmaceutical companies developing next-generation antibacterial treatments.

Application

• Pharmaceutical Active Ingredient (API): Serves as the core active component in the formulation of finished antibiotic drugs.
• Antimicrobial Research: Used in preclinical and clinical research to study efficacy against Gram-positive and Gram-negative bacteria, particularly those causing respiratory tract infections.
• Drug Development: A key intermediate for pharmaceutical companies developing new fluoroquinolone-based therapies with improved safety and resistance profiles.
• Reference Standard: Employed as a high-purity analytical standard in quality control laboratories for method development and validation.
• Combinatorial Chemistry: Utilized in research to create novel analogs and derivatives for structure-activity relationship (SAR) studies.

Basic Information

Product Name	Zabofloxacin
CAS No.	219680-11-2
Molecular Formula	C₁₉H₂₁FN₄O₄
Molecular Weight	388.39 g/mol
Synonyms	DW-224a; Zabofloxacin hydrochloride; (3S)-9-Fluoro-3-methyl-10-(4-methylpiperazin-1-yl)-7-oxo-2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylic acid; DW224a; ACT-387042; Zabofloxacin (base)
EINECS	Contact for details

Quality Control

Our Zabofloxacin is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, residual solvent analysis, and identification by IR and NMR spectroscopy, to ensure it meets stringent specifications for pharmaceutical R&D use. Certificates of Analysis (COA) documenting all test results are provided to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption, which may affect stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥98.0%
Related Substances (HPLC)	Total impurities ≤2.0% Any single unknown impurity ≤0.5%
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.