Description

n-[(9H-Fluoren-9-Ylmethoxy)Carbonyl]-L-Phenylalanylglycylglycine is a specialized Fmoc-protected tripeptide building block, essential for solid-phase peptide synthesis (SPPS). This compound provides a critical intermediate for the controlled assembly of complex peptides and peptidomimetics in research and pharmaceutical development. It is primarily utilized by researchers and manufacturers in the fields of medicinal chemistry, biochemistry, and drug discovery for creating novel therapeutic agents and biochemical probes.

Application

• Solid-Phase Peptide Synthesis (SPPS): A key intermediate for the sequential addition of amino acids in automated or manual peptide synthesis.
• Pharmaceutical Research: Used in the discovery and development of peptide-based drugs, including hormone analogs and enzyme inhibitors.
• Bioconjugation: Serves as a linker or spacer molecule for attaching peptides to other biomolecules, surfaces, or carriers.
• Biochemical Probe Development: Incorporated into peptides used to study protein-protein interactions, enzyme activity, and cellular signaling pathways.
• Combinatorial Chemistry Libraries: A building block for generating diverse peptide libraries for high-throughput screening against biological targets.
• Academic Research: Employed in university and institutional labs for fundamental studies in peptide structure, function, and stability.

Basic Information

Product Name	n-[(9H-Fluoren-9-Ylmethoxy)Carbonyl]-L-Phenylalanylglycylglycine
CAS No.	219677-70-0
Molecular Formula	C28H27N3O6
Molecular Weight	501.53 g/mol
Synonyms	Fmoc-Phe-Gly-Gly-OH; Fmoc-L-Phenylalanylglycylglycine; N-[(9-Fluorenylmethoxy)carbonyl]-L-phenylalanylglycylglycine; Fmoc-Phenylalanine-Glycine-Glycine; Fmoc-FGG-OH; (9H-Fluoren-9-yl)methyl N-[(2S)-1-[[2-(glycylamino)-2-oxoethyl]amino]-1-oxo-3-phenylpropan-2-yl]carbamate; Fmoc-Phe-Gly-Gly; N-Fmoc-L-phenylalanylglycylglycine
EINECS	Contact for details

Quality Control

Our n-[(9H-Fluoren-9-Ylmethoxy)Carbonyl]-L-Phenylalanylglycylglycine is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for sensitive research and development applications. A comprehensive Certificate of Analysis (COA) detailing purity, chiral integrity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Specific Rotation	Contact for details
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm
Residual Solvents	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.