Description

2-[(3-Fluorobenzyl)Oxy]-5-Nitrobenzaldehyde is a high-purity, specialized organic building block of significant interest in advanced chemical synthesis. Its unique molecular structure, featuring both a nitro and a fluorinated benzyloxy substituent, makes it a critical intermediate for the development of novel active compounds. This product is essential for research and development chemists and process scale-up teams in the pharmaceutical and agrochemical industries seeking to introduce specific functionalities into complex molecules.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, particularly those targeting central nervous system (CNS) disorders, due to the fluorine atom's role in modulating bioavailability and metabolic stability.
• Agrochemical Research: Used in developing new active ingredients for crop protection products, where the nitro and aldehyde groups serve as handles for constructing heterocyclic systems common in herbicides and fungicides.
• Ligand and Catalyst Development: Serves as a starting material for creating sophisticated ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science: Employed in the synthesis of organic electronic materials and specialty polymers, where its electron-withdrawing groups can fine-tune electronic properties.
• Chemical Biology Probes: Utilized to build fluorescent tags or photoaffinity labels for studying biological processes and protein interactions.

Basic Information

Product Name	2-[(3-Fluorobenzyl)Oxy]-5-Nitrobenzaldehyde
CAS No.	219539-49-8
Molecular Formula	C14H10FNO4
Molecular Weight	275.23 g/mol
Synonyms	5-Nitro-2-[(3-fluorobenzyl)oxy]benzaldehyde; 2-[(3-Fluorophenyl)methoxy]-5-nitrobenzaldehyde; 3-Fluorobenzyl 5-nitro-2-formylphenyl ether; 2-(3-Fluorobenzyloxy)-5-nitrobenzaldehyde; 5-Nitro-2-(3-fluorobenzyloxy)benzaldehyde; Benzaldehyde, 2-[(3-fluorobenzyl)oxy]-5-nitro-; 219539-49-8
EINECS	Contact for details

Quality Control

Our 2-[(3-Fluorobenzyl)Oxy]-5-Nitrobenzaldehyde is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and heavy metals. We provide a detailed Certificate of Analysis (COA) with every shipment to ensure traceability and compliance with your research or production standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its light-sensitive and easily oxidized nature, it is recommended to store the material under an inert atmosphere (e.g., nitrogen or argon) for long-term stability. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Yellow to pale brown crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.